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  2. Bevacizumab - Wikipedia

    en.wikipedia.org/wiki/Bevacizumab

    Bevacizumab, sold under the brand name Avastin among others, is a monoclonal antibody medication used to treat a number of types of cancers and a specific eye disease. [30] [28] For cancer, it is given by slow injection into a vein (intravenous) and used for colon cancer, lung cancer, ovarian cancer, glioblastoma, hepatocellular carcinoma, and renal-cell carcinoma. [31]

  3. List of drugs known for off-label use - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_known_for...

    Other non-FDA-approved uses for prazosin include the treatment of Raynaud's disease and poisoning due to scorpion venom. Propranolol (Inderal) for performance anxiety: propranolol is a non-selective beta-blocker used for the treatment of hypertension and the prophylaxis of angina pectoris. In 1991, a published study showed that a single dose of ...

  4. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. [ 3 ]

  5. Sacubitril/valsartan - Wikipedia

    en.wikipedia.org/wiki/Sacubitril/valsartan

    Sacubitril/valsartan, sold under the brand name Entresto among others, is a fixed-dose combination medication for use in heart failure.It consists of the neprilysin inhibitor sacubitril and the angiotensin receptor blocker valsartan.

  6. Pfizer's Avastin biosimilar wins FDA approval - AOL

    www.aol.com/news/pfizers-avastin-biosimilar-wins...

    Pfizer's Zirabev received approval for the treatment of five types of cancer, including colorectal and lung cancers, it said. In 2017, U.S.-based Amgen Inc's Mvasi was approved by the FDA as the ...

  7. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    Treatment of adults with previously treated, unresectable or metastatic HER2-positive (IHC3+) biliary tract cancer as detected by an FDA approved test [2] Zenocutuzumab: Treatment of adults with advanced, unresectable or metastatic non-small cell lung cancer harboring a neuregulin 1 (NRG1) gene fusion with disease progression on or after prior ...

  8. Angiogenesis inhibitor - Wikipedia

    en.wikipedia.org/wiki/Angiogenesis_inhibitor

    After a series of clinical trials in 2004, Avastin was approved by the FDA, becoming the first commercially available anti-angiogenesis drug. FDA approval of Avastin for breast cancer treatment was later revoked on November 18, 2011.

  9. Angiotensin II receptor blocker - Wikipedia

    en.wikipedia.org/wiki/Angiotensin_II_receptor...

    Angiotensin II receptor blockers are used primarily for the treatment of hypertension where the patient is intolerant of ACE inhibitor therapy primarily because of persistent and/or dry cough. [ 6 ] [ 7 ] They do not inhibit the breakdown of bradykinin or other kinins , and are thus only rarely associated with the persistent dry cough and/or ...