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As malakoplakia is a condition associated with chronic cystitis, it usually presents itself as a cystitis condition. The following investigations may help in making the diagnosis of malakoplakia: [citation needed] Urinalysis which indicates presence of bacteria and white blood cells. Urine culture
M-G bodies are a pathognomonic feature of malakoplakia, an inflammatory condition that affects the genitourinary tract. They were initially discovered in 1902 by Leonor Michaelis and Carl Gutmann. [citation needed] Michaelis-Gutmann bodies stain positive for von kossa (calcium), Prussian Blue (iron), and PAS diastase stain.
Malakoplakia; Malaria; Male pseudohermaphroditism due to 17-beta-hydroxysteroid dehydrogenase deficiency; Male pseudohermaphroditism due to 5-alpha-reductase 2 deficiency
Many skin conditions require a skin biopsy for confirmation of the diagnosis. With several of these conditions there are features within the cells contained in the skin biopsy specimen that have elements in their cytoplasm or nucleus that have a characteristic appearance unique to the condition.
For instance, the Michaelis-Gutmann body, a characteristic histological finding in malakoplakia, exhibits a targetoid or "bull's-eye" appearance under light microscopy. [ 4 ] [ 5 ] These intracellular and extracellular inclusions, composed of mineralized bacterial debris, illustrate how the targetoid pattern can manifest at both clinical and ...
Urinary bladder disease includes urinary bladder inflammation such as cystitis, bladder rupture and bladder obstruction (tamponade).Cystitis is common, sometimes referred to as urinary tract infection (UTI) caused by bacteria, bladder rupture occurs when the bladder is overfilled and not emptied while bladder tamponade is a result of blood clot formation near the bladder outlet.
The xanthogranulomatous type of inflammation is most-commonly seen in pyelonephritis and cholecystitis, although it has more recently been described in an array of other locations including bronchi, lung, endometrium, vagina, fallopian tubes, ovary, testis, epididymis, stomach, colon, ileum, pancreas, bone, lymph nodes, bladder, adrenal gland, abdomen and muscle. [5]
S. Saber shin; Saddle nose; Scarlet fever; Scrub typhus; Septic sore; Serpiginous ulceration of the groin; Shigellosis; Soft chancre; Spotted fever rickettsiosis