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n/a Ensembl ENSG00000255717 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a Wikidata View/Edit Human Small nucleolar RNA host gene 1 is a non-protein coding RNA that in humans is encoded by the SNHG1 gene. Function This locus represents a small nucleolar RNA host gene that produces multiple alternatively spliced long non-coding RNAs ...
The RNA component of human telomerase (hTERC) contains an H/ACA domain for pre-RNP formation and nucleolar localization of the telomerase RNP itself. [13] The H/ACA snoRNP has been implicated in the rare genetic disease dyskeratosis congenita (DKC) due to its affiliation with human telomerase.
U56 was originally cloned from HeLa cells and is predicted to guide the 2'O-ribose methylation of 18S ribosomal RNA (rRNA) residue C517. [2] [3] In the human genome U56 is encoded in the introns of the same host gene as several other snoRNAs (C/D box snoRNAs U57, U86 and HBII-55, and the H/ACA box snoRNA ACA51). [3]
U32 is encoded within intron 2 of the ribosomal protein L13 gene in human and mouse [2] and is predicted to guide the 2'O-ribose methylation of both 18S ribosomal RNA (rRNA) residue G1328 and 28S rRNA residue A1511. [2] [3] U32A share the same host gene with the C/D box snoRNAs U33, U34 and U35A (RPL13A). [3]
U43 is encoded in intron 1 of the ribosomal protein L3 gene in human and cow. [2] Three other snoRNAs ( U82, U83a and U83b) are also encoded in the same host gene but from different introns. [2] The Arabidopsis thaliana homologue is called snoR41 in the public sequence databases (Genbank). The rice homologue is expressed from a cluster also ...
U52 was originally cloned from HeLa cells and is predicted to guide the 2'O-ribose methylation of 28S ribosomal RNA (rRNA) residue U3904. [2] [3] U52 and the C/D box snoRNA U48 are encoded in the introns of the same host gene (C6orf48). [3]
The U76/SNORD76 snoRNA is found in an intron of the uRNA host gene (UHG) growth arrest specific 5 (GAS5) transcript gene. [ 5 ] snoRNAs Z20 and U76 snoRNAs show clear similarity to U24. An experiment that looked at 22 different non-small-cell lung cancer tissues found that SNORD33 , SNORD66 and SNORD76 were over-expressed relative to matched ...
It is found within intron 2 of the L21 ribosomal protein gene. The H/ACA box snoRNA ACA27 is found in the same host gene within a different intron. [3] U102 is predicted to guide the 2'O-ribose methylation of 28S ribosomal RNA (rRNA) residue G4020. [3]