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Merrill said that adult children or spouses of people with Alzheimer’s may come in for testing without symptoms, but in general, most clinic patients seek care when symptoms appear.
It is an uncommon form of Alzheimer's, accounting for only 5–10% of all Alzheimer's cases. About 60% have a positive family history of Alzheimer's and 13% of them are inherited in an autosomal dominant manner. Most cases of early-onset Alzheimer's share the same traits as the "late-onset" form and are not caused by known genetic mutations.
In people with Alzheimer's disease, the increasing impairment of learning and memory eventually leads to a definitive diagnosis. In a small percentage, difficulties with language, executive functions, perception ( agnosia ), or execution of movements ( apraxia ) are more prominent than memory problems. [ 41 ]
Avoidant personality disorder (AvPD), or anxious personality disorder, is a cluster C personality disorder characterized by excessive social anxiety and inhibition, fear of intimacy (despite an intense desire for it), severe feelings of inadequacy and inferiority, and an overreliance on avoidance of feared stimuli (e.g., self-imposed social isolation) as a maladaptive coping method. [1]
A new study distinguishes between two distinct phases of Alzheimer's disease: an early, 'stealth' one without symptoms, and a second phase that aggressively damages the brain.
Researchers have identified a new biomarker for Alzheimer's disease, which could help doctors diagnose it before symptoms start showing.
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