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Cushing reflex (also referred to as the vasopressor response, the Cushing effect, the Cushing reaction, the Cushing phenomenon, the Cushing response, or Cushing's Law) is a physiological nervous system response to increased intracranial pressure (ICP) that results in Cushing's triad of increased blood pressure, irregular breathing, and bradycardia. [1]
Intracranial pressure (ICP) is the pressure exerted by fluids such as cerebrospinal fluid (CSF) inside the skull and on the brain tissue. ICP is measured in millimeters of mercury and at rest, is normally 7–15 mmHg for a supine adult. This equals to 9–20 cmH 2 O, which is a common scale used in lumbar punctures. [1]
Sinus bradycardia is a sinus rhythm with a reduced rate of electrical discharge from ... increased intracranial pressure; ... new symptoms such as chest pain ...
Bradycardia may be associated with symptoms of fatigue, dyspnea, dizziness, confusion, and frank syncope due to reduced forward blood flow to the brain, lungs, and skeletal muscle. [6] The types of symptoms often depend on the etiology of the slow heart rate, classified by the anatomic location of a dysfunction within the cardiac conduction ...
Cushing's triad of Increased Intracranial Pressure: Bradycardia, Bradypnea, Hypertension: Head injuries Danny's Triad: Painful urination, testicular pain, diarrhea: Chlamydia Dieulafoy's triad: hyperesthesia of the skin, exquisite tenderness and guarding over McBurney's point: Acute appendicitis: Dietl's crisis
Neurogenic shock is a distributive type of shock resulting in hypotension (low blood pressure), often with bradycardia (slowed heart rate), caused by disruption of autonomic nervous system pathways. [1] It can occur after damage to the central nervous system, such as spinal cord injury and traumatic brain injury.
A high pulse pressure combined with bradycardia and an irregular breathing pattern is associated with increased intracranial pressure, a condition called Cushing's triad seen in people after head trauma with increased intracranial pressure. [16] Common causes of widening pulse pressure include: [3] [medical citation needed] Anemia; Aortic ...
Cardiovascular and pulmonary symptoms may also be present as the brain loses function, but might also be associated with bleeding. These symptoms are known as Cushing's Triad: hypertension (with widening pulse pressure), irregular respirations (commonly Cheyne-Stokes), bradycardia and in severe cases cardiac arrest. [3] [4]
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