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The Protein database is a collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB. Protein sequences are the fundamental determinants of biological structure and function.
NCBI's Protein resources include protein sequences and structures and related comparison and visualization tools, as well as databases and tools to predict and analyze functional domains. How to. Retrieve all protein sequences for an organism or taxon; Find the function of a protein; Find a gene homolog; View a protein 3D structure; more...
A collection of related protein sequences (clusters), consisting of Reference Sequence proteins encoded by complete prokaryotic and organelle plasmids and genomes. The database provides easy access to annotation information, publications, domains, structures, external links, and analysis tools.
The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches.
BlastP simply compares a protein query to a protein database. PSI-BLAST allows the user to build a PSSM (position-specific scoring matrix) using the results of the first BlastP run. PHI-BLAST performs the search but limits alignments to those that match a pattern in the query.
A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
Entrez covers over 20 databases including the complete protein sequence data from PIR-International, PRF, Swiss-Prot, and PDB and nucleotide sequence data from GenBank that includes information from EMBL and DDBJ.
PROTEIN SEQUENCE DATABASES. Thanks to the Human Genome Project and other sequencing efforts, new sequences have been generated at a prodigious rate. These sequences provide a rich information source and are the core of the revolutionary movement toward “large-scale biology.”
A graphical analysis tool that finds all open reading frames in a user's sequence or in a sequence already in the database. Sixteen different genetic codes can be used. The deduced amino acid sequence can be saved in various formats and searched against protein databases using BLAST.
Search GenBank for sequence identifiers and annotations with Entrez Nucleotide. Search and align GenBank sequences to a query sequence using BLAST (Basic Local Alignment Search Tool). See BLAST info for more information about the numerous BLAST databases. Search, link, and download sequences programatically using NCBI e-utilities.