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Schistosomiasis, also known as snail fever, bilharzia, and Katayama fever [1] [2] [9] is a disease caused by parasitic flatworms called schistosomes. [5] It affects the urinary tract or the intestines. [5] Symptoms include abdominal pain, diarrhea, bloody stool, or blood in the urine. [5]
Clinical symptoms are caused by the eggs. As the leading cause of schistosomiasis in the world, it is the most prevalent parasite in humans. It is classified as a neglected tropical disease. As of 2021, the World Health Organization reports that 251.4 million people have schistosomiasis and most of it is due to S. mansoni. [1]
Schistosoma is a genus of trematodes, commonly known as blood flukes.They are parasitic flatworms responsible for a highly significant group of infections in humans termed schistosomiasis, which is considered by the World Health Organization to be the second-most socioeconomically devastating parasitic disease (after malaria), infecting millions worldwide.
Schistosoma japonicum is an important parasite and one of the major infectious agents of schistosomiasis.This parasite has a very wide host range, infecting at least 31 species of wild mammals, including nine carnivores, 16 rodents, one primate (human), two insectivores and three artiodactyls and therefore it can be considered a true zoonosis.
Schistosomiasis was first reported in the Mekong River's Lower Basin region in 1957, from Laotian island of Khong to Cambodian province of Kratié, specifically. [2] It was believed that the cause of these cases was Schistosoma japonicum until 1978, when Neotricula aperta was discovered and it was determined that the Schistosome was a unique species, Schistosoma mekongi. [2]
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Schistosoma intercalatum's life cycle is very similar to that of S. haematobium, except for some key differences. To start the life cycle, the human host releases eggs with its feces. In water, the eggs hatch to become miracidia, which penetrate the freshwater snail intermediate host. [5]
"It’s a new take on life." Looney is the fifth patient to be given a gene-edited pig organ since 2022 — and the third to receive a kidney — per The New York Times.