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  2. Neuromuscular disease - Wikipedia

    en.wikipedia.org/wiki/Neuromuscular_disease

    Further causes of neuromuscular diseases are: Polymyositis. Inflammatory muscle disorders. Polymyalgia rheumatica (or "muscle rheumatism") is an inflammatory condition that mainly occurs in the elderly; it is associated with giant-cell arteritis (It often responds to prednisolone). [18] Polymyositis is an autoimmune condition in which the ...

  3. Aging movement control - Wikipedia

    en.wikipedia.org/wiki/Aging_movement_control

    The old trained men have succinate dehydrogenase activities within their type IIa muscle fibers similar to those in young men and twofold higher than in old normal fit men. [ 20 ] Neural changes like reduced motor unit discharge rates, increased variability of motor unit discharge activity, altered recruitment and derecruitment behavior mediate ...

  4. Fibromyalgia - Wikipedia

    en.wikipedia.org/wiki/Fibromyalgia

    Fibromyalgia is predominantly a chronic pain disorder. [12] According to the NHS, widespread pain is one major symptom, which could feel like an ache, a burning sensation, or a sharp, stabbing pain. [42] Patients are also highly sensitive to pain, and the slightest touch can cause pain.

  5. Adenosine monophosphate deaminase deficiency type 1

    en.wikipedia.org/wiki/Adenosine_monophosphate...

    Muscle pain. Muscle pain from MADD is not well understood, but is partially due to high levels of lactate. Increased levels of free adenosine temporarily decrease pain, allowing over-exertion without awareness. [5] The over exertion can cause mild to severe cases of rhabdomyolysis, which is painful. [6] Adenosine mediates pain through adenosine ...

  6. Frailty syndrome - Wikipedia

    en.wikipedia.org/wiki/Frailty_syndrome

    Frail elderly patients (score of 4 or 5) have even worse outcomes, with the risk of being discharged to a nursing home rising to twenty times the rate for non-frail elderly people. Another tool that has been used to predict frailty outcome post-surgery is the Modifies Frailty Index, or mFI-5. This scale consists of 5 key co-morbidities: [59]

  7. Inclusion body myositis - Wikipedia

    en.wikipedia.org/wiki/Inclusion_body_myositis

    In people with sIBM, the muscle cells display "flags" telling the immune system that they are infected or damaged (the muscles ubiquitously express MHC class I antigens) and this immune process leads to the death of muscle cells. The chronic stimulation of these antigens also causes stress inside the muscle cell in the endoplasmic reticulum (ER ...

  8. Weakness - Wikipedia

    en.wikipedia.org/wiki/Weakness

    The causes are many and can be divided into conditions that have true or perceived muscle weakness. True muscle weakness is a primary symptom of a variety of skeletal muscle diseases, including muscular dystrophy and inflammatory myopathy. It occurs in neuromuscular junction disorders, such as myasthenia gravis. [citation needed]

  9. Myofascial pain syndrome - Wikipedia

    en.wikipedia.org/wiki/Myofascial_pain_syndrome

    The cause is believed to be muscle tension or spasms within the affected musculature. [1] Diagnosis is based on the symptoms and possible sleep studies. [1] Treatment may include pain medication, physical therapy, mouth guards, and occasionally benzodiazepine. [1] It is a relatively common cause of temporomandibular pain. [1]