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  2. Myotonic dystrophy - Wikipedia

    en.wikipedia.org/wiki/Myotonic_dystrophy

    Myotonic dystrophy affects about 1 in 2,100 people, [4] a number that was long estimated to be much lower (often cited as 1 in 8,000), reflecting that not all patients have immediate symptoms and, once they do have symptoms, the long time it typically takes to get to the right diagnosis. [1]

  3. Myotonia - Wikipedia

    en.wikipedia.org/wiki/Myotonia

    Myotonia is the defining symptom of many channelopathies (diseases of ion channel transport) such as myotonia congenita, paramyotonia congenita and myotonic dystrophy. [3] [4] Brody disease (a disease of ion pump transport) has symptoms similar to myotonia congenita, however, the delayed muscle relaxation is pseudo-myotonia as the EMG is normal ...

  4. Muscular dystrophy - Wikipedia

    en.wikipedia.org/wiki/Muscular_Dystrophy

    The cardiac problems that occur with Emery–Dreifuss muscular dystrophy (EDMD) and myotonic muscular dystrophy may require a pacemaker. [29] The myotonia (delayed relaxation of a muscle after a strong contraction) occurring in myotonic muscular dystrophy may be treated with medications such as quinine. [30]

  5. Myotonia congenita - Wikipedia

    en.wikipedia.org/wiki/Myotonia_congenita

    Myotonia congenita is a congenital neuromuscular channelopathy that affects skeletal muscles (muscles used for movement). It is a genetic disorder.The hallmark of the disease is the failure of initiated contraction to terminate, often referred to as delayed relaxation of the muscles and rigidity. [1]

  6. Insulin Resistance: From Symptoms to Treatment - AOL

    www.aol.com/insulin-resistance-symptoms...

    A number of genetic conditions have been linked to the development of insulin resistance, including myotonic dystrophy, ataxia-telangiectasia, Alstrom syndrome, Rabson-Mendenhall syndrome, Werner ...

  7. Gowers's sign - Wikipedia

    en.wikipedia.org/wiki/Gowers's_sign

    Gowers's sign is classically seen in Duchenne muscular dystrophy where it is mostly evident at 4–6 years, but also presents itself in centronuclear myopathy, myotonic dystrophy and various other conditions associated with proximal muscle weakness, including Becker muscular dystrophy, dermatomyositis and Pompe disease. For this maneuver, the ...

  8. Myotonin-protein kinase - Wikipedia

    en.wikipedia.org/wiki/Myotonin-protein_kinase

    Myotonic dystrophy (DM) 1 is an autosomal dominant neuromuscular disorder affecting approximately 1 in 8000 individuals. Affected individuals display a wide range of symptoms including myotonia, skeletal muscle weakness and wasting, cardiac conduction abnormalities, and cataracts.

  9. Anticipation (genetics) - Wikipedia

    en.wikipedia.org/wiki/Anticipation_(genetics)

    In most cases, an increase in the severity of symptoms is also noted. Anticipation is common in trinucleotide repeat disorders, such as Huntington's disease and myotonic dystrophy, where a dynamic mutation in DNA occurs. All of these diseases have neurological symptoms.

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