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A nucleic acid test (NAT) is a technique used to detect a particular nucleic acid sequence and thus usually to detect and identify a particular species or subspecies of organism, often a virus or bacterium that acts as a pathogen in blood, tissue, urine, etc. NATs differ from other tests in that they detect genetic materials (RNA or DNA) rather ...
Nucleic acid-based tests (NAT) Nucleic-acid-based tests amplify and detect one or more of several target sequences located in specific HIV genes, such as HIV-I GAG, HIV-II GAG, HIV-env, or the HIV-pol. [ 32 ] [ 33 ] Since these tests are relatively expensive, the blood is screened by first pooling some 8–24 samples and testing these together ...
Various viral load tests might be used. One way to classify tests is by whether it is a nucleic acid test or non-nucleic acid test. [2] Variation in cost and the time it takes to get a result may be factors in selecting the type of test used. [3]
Transcription-mediated amplification (TMA) is an isothermal (performed at constant temperature), single-tube nucleic acid amplification system utilizing two enzymes, RNA polymerase and reverse transcriptase. "Amplification" means creating many more copies of a strand of nucleic acid than was present at first, in order to readily detect it or ...
A 2010 review study by Puren et al. [2] categorizes viral load testing into three types: (1) nucleic acid amplification based tests (NATs or NAATs) commercially available in the United States with Food and Drug Administration (FDA) approval, or on the market in the European Economic Area (EEA) with the CE marking; (2) "Home–brew" or in-house NATs; (3) non-nucleic acid-based test.
These fall into three basic varieties: antibody tests, nucleic acid tests (NAT), and surrogate tests. Antibody tests look for the immune system's response to the infection. Nucleic acid tests look for the genetic material of the virus itself. The third variety are tests that are not specific to the disease but look for other related conditions.
It produces test results in 5 minutes using its ID NOW portable testing system. [1] It also received EUA for its m2000-based laboratory nucleic acid test for COVID-19. [2] In April 2020, Abbott received EUA for its ARCHITECT IgG laboratory antibody test for COVID-19. [3] Also in April, Abbott's ID NOW test was reported to have sensitivity of 85 ...
The Xpert MTB/RIF is a cartridge-based nucleic acid amplification test (NAAT) for rapid tuberculosis diagnosis and rapid antibiotic sensitivity test.It is an automated diagnostic test that can identify Mycobacterium tuberculosis (MTB) DNA and resistance to rifampicin (RIF).