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Steatosis reflects an impairment of the normal processes of synthesis and elimination of triglyceride fat. Excess lipid accumulates in vesicles that displace the cytoplasm. When the vesicles are large enough to distort the nucleus, the condition is known as macrovesicular steatosis; otherwise, the condition is known as microvesicular steatosis ...
Fatty liver disease (FLD), also known as hepatic steatosis and steatotic liver disease (SLD), is a condition where excess fat builds up in the liver. [1] Often there are no or few symptoms. [ 1 ] [ 2 ] Occasionally there may be tiredness or pain in the upper right side of the abdomen . [ 1 ]
Metabolic dysfunction–associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), [a] is a type of chronic liver disease.This condition is diagnosed when there is excessive fat build-up in the liver (hepatic steatosis), and at least one metabolic risk factor.
Steatosis usually resolves after discontinuation of alcohol use. Continuation of alcohol use will result in a higher risk of progression of liver disease and cirrhosis. In patients with acute alcoholic hepatitis, clinical manifestations include fever, jaundice, hepatomegaly , and possible hepatic decompensation with hepatic encephalopathy ...
Cirrhosis is often preceded by hepatitis and fatty liver (steatosis), independent of the cause. If the cause is removed at this stage, the changes are fully reversible. [citation needed] The pathological hallmark of cirrhosis is the development of scar tissue that replaces normal tissue, which is normally organized into lobules.
The definition of a unit of alcohol ranges between 8 and 14 grams of pure ethanol depending on the country. [6] There is no agreement on definitions of a low, moderate or high dose of alcohol either. The U.S. National Institute on Alcohol Abuse and Alcoholism defines a moderate dose as alcohol intake up to two standard drinks or 28 grams for ...
Neuromodulation is the physiological process by which a given neuron uses one or more chemicals to regulate diverse populations of neurons. Neuromodulators typically bind to metabotropic, G-protein coupled receptors (GPCRs) to initiate a second messenger signaling cascade that induces a broad, long-lasting signal.
Maladjustment is a term used in psychology to refer the "inability to react successfully and satisfactorily to the demand of one's environment". [1] The term maladjustment can be referred to a wide range of social, biological and psychological conditions. [2] Maladjustment can be both intrinsic or extrinsic.