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Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. [1] Signs and symptoms may include vomiting , abdominal pain , deep gasping breathing , increased urination , weakness, confusion and occasionally loss of consciousness . [ 1 ]
Different labs use different formulas and procedures to calculate the anion gap, so the reference range (or "normal" range) from one lab isn't directly interchangeable with the range from another. The reference range provided by the particular lab that performed the testing should always be used to interpret the results. [ 3 ]
The most common causes of high anion gap metabolic acidosis are: ketoacidosis, lactic acidosis, kidney failure, and toxic ingestions. [3]Ketoacidosis can occur as a complication of diabetes mellitus (diabetic ketoacidosis), but can occur due to other disorders, such as chronic alcoholism and malnutrition.
In nephrology, the delta ratio, or "delta-delta" (denoted Δ/Δ), is a formula that can be used to evaluate whether a mixed acid–base disorder (metabolic acidosis) is present, and if so, assess its severity.
Metabolic acidosis is a serious electrolyte disorder characterized by an imbalance in the body's acid-base balance.Metabolic acidosis has three main root causes: increased acid production, loss of bicarbonate, and a reduced ability of the kidneys to excrete excess acids. [5]
Key Points from 24/7 Wall St.: The maximum Social Security check in 2025 is $5,108. There’s a maximum check because there is a cap on how much income is used to calculate benefits.
Diabetic ketoacidosis, in which high levels of acidic ketone bodies are produced; Lactic acidosis, due to anaerobic metabolism during heavy exercise or hypoxia; Chronic kidney failure, preventing excretion of acid and resorption and production of bicarbonate; Diarrhea, in which large amounts of bicarbonate are excreted
One’s biological age, which measures the body’s physiological state, may help predict who is at risk for developing colon polyps, a known risk factor for colorectal cancer.