Search results
Results from the WOW.Com Content Network
Albendazole is a broad-spectrum antihelmintic and antiprotozoal agent of the benzimidazole type. [3] It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases.
Benznidazole is an antiparasitic medication used in the treatment of Chagas disease. [2] While it is highly effective in early disease, the effectiveness decreases in those who have long-term infection. [3] It is the first-line treatment given its moderate side effects compared to nifurtimox. [1] It is taken by mouth. [2] Side effects are ...
It is a member of the benzimidazole family of medications for worms. [1] Triclabendazole was approved for medical use in the United States in 2019. [3] [4] It is on the World Health Organization's List of Essential Medicines. [5] For human use, it can be obtained from the World Health Organization. [2] It is also used in animals. [6]
Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the tapeworm genus Taenia (but not effective against Dipylidium caninum, a common dog tapeworm), pinworms, aelurostrongylus, paragonimiasis, strongyles, and strongyloides that can be administered to sheep, cattle, horses, fish, dogs, cats ...
Benzimidazole was discovered during research on vitamin B 12. The benzimidazole nucleus was found to be a stable platform on which drugs could be developed. [3] Benzimidazole is produced by condensation of o-phenylenediamine with formic acid, [4] or the equivalent trimethyl orthoformate: C 6 H 4 (NH 2) 2 + HC(OCH 3) 3 → C 6 H 4 N(NH)CH + 3 CH ...
The structure-activity relationship of the drug class has been explored to a reasonable extent. The optimal substitution pattern is fairly tightly defined (i.e. N,N-diethyl on the amine nitrogen, 4-ethoxy on the benzyl ring and 5-nitro on the benzimidazole ring), but even derivatives incorporating only some of these features are still potent opioids.
Under veterinary use, its brand name is Flutelmium which is a paste manufactured by Janssen Pharmaceutica N.V. used by veterinarians for protection against internal parasites and worms in dogs and cats. Other brand names are Flubenol, Biovermin, and Flumoxal. [5]
Mebendazole (MBZ), sold under the brand name Vermox among others, is a medication used to treat a number of parasitic worm infestations. [5] This includes ascariasis, pinworm infection, hookworm infections, guinea worm infections and hydatid disease, among others. [5] It has been used for treatment of giardiasis but is not a preferred agent.