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Primitive neuroectodermal tumor is a malignant (cancerous) neural crest tumor. [1] It is a rare tumor , usually occurring in children and young adults under 25 years of age. The overall 5 year survival rate is about 53%.
A phase III study of sunitinib treatment in well differentiated pNET that had worsened within the past 12 months (either advanced or metastatic disease) showed that sunitinib treatment improved progression-free survival (11.4 months vs. 5.5 months), overall survival, and the objective response rate (9.3% vs. 0.0%) when compared with placebo.
A central nervous system primitive neuroectodermal tumor, often abbreviated as PNET, supratentorial PNET, or CNS-PNET, [1] is one of the 3 types of embryonal central nervous system tumors (medulloblastoma, atypical teratoid rhabdoid tumor, and PNET). [2]
[8] [9] Treatment of PNETs is the same as extra-osseous Ewing’s sarcoma, with resection of the whole tumor alongside chemotherapy and radiation. Outcomes however are poor as PNET remains an aggressive cancer as a member of the Ewing Family of Tumors. [9]
Tumors that originate in the cerebellum or the surrounding region below the tentorium are, therefore, called infratentorial. Historically, medulloblastomas have been classified as a primitive neuroectodermal tumor (PNET), but it is now known that medulloblastoma is distinct from supratentorial PNETs and they are no longer considered similar ...
Neuroendocrine tumors ... is the first and only FDA approved antitumor therapy demonstrating a statistically significant progression-free survival benefit in a ...
A terminally ill single mom-of-two set up a GoFundMe page in the hopes of raising $5,000 to cover the expenses of her own funeral and support her children.Nevertheless, her heartbreaking story ...
Gastrinoma is the second most common functional pancreatic neuroendocrine tumor (pNET), with a yearly incidence of approximately 0.5 to 21.5 cases per a million of people worldwide. [5] Gastrinomas are located predominantly in the duodenum (70%) and pancreas (25%). [20]
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