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A much more convenient method for the synthesis of β-phenethylamine is the reduction of ω-nitrostyrene by lithium aluminium hydride in ether, whose successful execution was first reported by R. F. Nystrom and W. G. Brown in 1948. [23] Phenethylamine can also be produced via the cathodic reduction of benzyl cyanide in a divided cell. [24]
Naturally occurring phenethylamines are organic compounds which may be thought of as being derived from phenethylamine itself that are found in living organisms. Tyramine is a phenethylamine that occurs widely in plants [ 1 ] and animals , and is metabolized by various enzymes , including monoamine oxidases .
Substitutions to the phenethylamine molecule give rise to a group of compounds collectively known as substituted phenethylamines or phenethylamines. This is a set category . It should only contain pages that are about [substituted] phenethylamines or lists of [substituted] phenethylamines , as well as subcategories containing those things ...
Substituted phenethylamines (or simply phenethylamines) are a chemical class of organic compounds that are based upon the phenethylamine structure; [note 1] the class is composed of all the derivative compounds of phenethylamine which can be formed by replacing, or substituting, one or more hydrogen atoms in the phenethylamine core structure with substituents.
2C (2C-x) is a general name for the family of psychedelic phenethylamines containing methoxy groups on the 2 and 5 positions of a benzene ring. [1] [2] [3] Most of these compounds also carry lipophilic substituents at the 4 position, usually resulting in more potent and more metabolically stable and longer acting compounds. [4]
[3] [4] [10] Trace aminergic hypo-function is particularly relevant to ADHD, since urinary and plasma phenethylamine concentrations are significantly lower in individuals with ADHD relative to controls and the two most commonly prescribed drugs for ADHD, amphetamine and methylphenidate, increase phenethylamine biosynthesis in treatment ...
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Chemically, phenyethanolamine is an aromatic compound, an amine, and an alcohol. The amino-group makes this compound a weak base , capable of reacting with acids to form salts. Two common salts of phenylethanolamine are the hydrochloride, C 8 H 11 NO.HCl, m.p. 212 °C, [ 6 ] and the sulfate, (C 8 H 11 NO) 2 .H 2 SO 4 , m.p. 239–240 °C.