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White-bellied agouti A W mice have agouti coloration, with hairs that are black at the tips, then yellow, then black again, and white to tan bellies. [4] Agouti A looks like A W but the belly is dark like the back. [4] Black and tan a t causes a black back with a tan belly. A/a t heterozygotes look like A W mice. [4]
Agouti-signaling protein is a protein that in humans is encoded by the ASIP gene. [5] [6] It is responsible for the distribution of melanin pigment in mammals.[7] [8] Agouti interacts with the melanocortin 1 receptor to determine whether the melanocyte (pigment cell) produces phaeomelanin (a red to yellow pigment), or eumelanin (a brown to black pigment). [9]
Randy Jirtle (born November 9, 1947) is an American biologist noted for his research in epigenetics, the branch of biology that deals with inherited information that does not reside in the nucleotide sequence of DNA. [1] Jirtle retired from Duke University, Durham, NC in 2012.
The agouti (/ ə ˈ ɡ uː t iː / ⓘ, ə-GOO-tee) or common agouti is many of several rodent species of the genus Dasyprocta. They are native to Central America, ...
A cat hair showing agouti coloration A domestic rabbit with agouti coloration. Agouti is a type of fur coloration in which each hair displays two or more bands of pigmentation. [1] [2] The overall appearance of agouti fur is usually gray or dull brown, [3] although dull yellow is also possible.
Mouse Genome Informatics (MGI) is a free, online database and bioinformatics resource hosted by The Jackson Laboratory, with funding by the National Human Genome Research Institute (NHGRI), the National Cancer Institute (NCI), and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). [1]
Punnett square for the agouti gene in mice, demonstrating a recessive lethal allele. [2] Lethal alleles were first discovered by Lucien Cuénot in 1905 while studying the inheritance of coat colour in mice. The agouti gene in mice is largely responsible for determining coat colour. The wild-type allele produces a blend of yellow and black ...
Dasyproctidae is a family of large South American rodents, comprising the agoutis and acouchis. [1] Their fur is a reddish or dark colour above, with a paler underside. They are herbivorous, often feeding on ripe fruit that falls from trees. They live in burrows, and, like squirrels, will bury some of their food for later use. [2]