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Pertussis vaccine is a vaccine that protects against whooping cough (pertussis). [ 1 ] [ 2 ] There are two main types: whole-cell vaccines and acellular vaccines. [ 1 ] [ 2 ] The whole-cell vaccine is about 78% effective while the acellular vaccine is 71–85% effective.
Whooping cough (/ ˈ h uː p ɪ ŋ / or / ˈ w uː p ɪ ŋ /), also known as pertussis or the 100-day cough, is a highly contagious, vaccine-preventable bacterial disease. [1] [10] Initial symptoms are usually similar to those of the common cold with a runny nose, fever, and mild cough, but these are followed by two or three months of severe coughing fits. [1]
Preventable with vaccine and PEP but once symptoms manifest, there is no cure and the CFR is greater than 99%. 4 known people who survived were simply vaccinated too late, [5] after symptoms started; more recently, at least 3 individuals have survived after being placed in a medically induced coma, however this protocol has since been disputed. [6]
The shingles vaccine is a two-dose series and provides protection for at least seven years, Tonizzo said. “It’s safe in everyone and is 90% to 95% effective.
In the 1990s, the US changed the type of vaccines used to prevent pertussis, moving from a whole-cell vaccine that caused children to spike fevers and experience other worrisome symptoms after ...
Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus bacterium of the genus Bordetella, and the causative agent of pertussis or whooping cough. Its virulence factors include pertussis toxin , adenylate cyclase toxin , filamentous haemagglutinin , pertactin , fimbria , and tracheal cytotoxin .
RSV causes over 177,000 hospitalizations and 14,000 deaths in the United States annually, while over 1 million people develop shingles every year in the country.
The DPT vaccine or DTP vaccine is a class of combination vaccines to protect against three infectious diseases in humans: diphtheria, pertussis (whooping cough), and tetanus (lockjaw). [7] The vaccine components include diphtheria and tetanus toxoids , and either killed whole cells of the bacterium that causes pertussis or pertussis antigens .