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This is an accepted version of this page This is the latest accepted revision, reviewed on 25 January 2025. Device to vaporize substances for inhalation A vaporization heat wand and vaporization chamber bowl used to deliver vapor through a water pipe A vaporizer or vaporiser, colloquially known as a vape, is a device used to vaporize substances for inhalation. Plant substances can be used ...
A 2018 Cochrane review found that, in rare cases, nicotine replacement therapy can cause non-ischemic chest pain (i.e., chest pain that is unrelated to a heart attack) and heart palpitations, but does not increase the incidence of serious cardiac adverse events (i.e., myocardial infarction, stroke, and cardiac death) relative to controls.
When trying to quit smoking with vaping a base containing nicotine, symptoms of withdrawal can include irritability, restlessness, poor concentration, anxiety, depression, and hunger. [152] The changes in the brain cause a nicotine user to feel abnormal when not using nicotine. [201]
Vaping-associated pulmonary injury (VAPI), [4] also known as vaping-associated lung injury (VALI) [1] or e-cigarette, or vaping, product use associated lung injury (E/VALI), [2] [a] is an umbrella term, [15] [16] used to describe lung diseases associated with the use of vaping products that can be severe and life-threatening. [3]
The nicotine levels in the e-cigarette vapor also varies greatly either from puff-to-puff or among devices of the same company. [1] Nicotine intake across users using same device or liquid varies substantially. [67] Puffing characteristics differ between smoking and vaping. [68] Vaping typically require more 'suck' than cigarette smoking. [69]
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
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Nicotine may result in adverse effects to the neurological growth of the fetus. [65] Nicotine can lead to vasoconstriction of uteroplacental vessels, which reduces the delivery of both nutrients and oxygen to the fetus. As a result, nutrition is re-distributed to prioritize vital organs, such as the heart and the brain, at the cost of less ...