Search results
Results from the WOW.Com Content Network
An amino acid transporter is a membrane transport protein that transports ... Families. There are several families that function in amino acid transport, some of ...
A transport protein (variously referred to as a transmembrane pump, transporter, escort protein, acid transport protein, cation transport protein, or anion transport protein) is a protein that serves the function of moving other materials within an organism. Transport proteins are vital to the growth and life of all living things.
A membrane transport protein is a membrane protein involved in the movement of ions, small molecules, and macromolecules, such as another protein, across a biological membrane. Transport proteins are integral transmembrane proteins ; that is they exist permanently within and span the membrane across which they transport substances.
The portion of the membrane proteins that are attached to the lipid bilayer (see annular lipid shell) consist mostly of hydrophobic amino acids. [13] Membrane proteins which have hydrophobic surfaces, are relatively flexible and are expressed at relatively low levels. This creates difficulties in obtaining enough protein and then growing crystals.
The amino acid transporter functions to move essential amino acids into the intestinal epithelium, placenta, and blood-brain barrier for cellular processes such as metabolism and cell signaling. [22] The transporter is of particular significance in the central nervous system as it provides the necessary amino acids for protein synthesis and ...
A "2 TMS" protein has 2 transmembrane segments) to give 6 TMS proteins. ABC2 exporters evolved by intragenic duplication of a 3 TMS precursor, and ABC3 exporters evolved from a 4 TMS precursor which duplicated either extragenicly to give two 4 TMS proteins, both required for transport function, or intragenicly to give 8 or 10 TMS proteins.
Heterodimeric amino-acid transporters are a family of transport proteins that facilitate the transport of certain amino acids across cell membranes. [1] Each comprises a light and a heavy protein subunit. Transport activity happens in the light. The following table lists the members of this family:
The two halves of the protein pack against each other in a clam-shell fashion, sealing via interactions at the ends of the transmembrane helices and extracellular loops. [ 7 ] [ 8 ] This forms a large aqueous cavity at the center of the membrane, which is alternatively open to the cytoplasm or periplasm /extracellular space.