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2. Parkinson's disease - Wikipedia

   en.wikipedia.org/wiki/Parkinson's_disease

   As of 2022, no disease-modifying drugs (drugs that target the causes or damage) are approved for Parkinson's, so this is a major focus of Parkinson's research. [ 262 ] [ 263 ] Active research directions include the search for new animal models of the disease and studies of the potential usefulness of gene therapy , stem cell transplants, and ...

3. MPTP - Wikipedia

   en.wikipedia.org/wiki/MPTP

   MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is an organic compound.It is classified as a tetrahydropyridine.It is of interest as a precursor to the monoaminergic neurotoxin MPP +, which causes permanent symptoms of Parkinson's disease by destroying dopaminergic neurons in the substantia nigra of the brain.

4. Signs and symptoms of Parkinson's disease - Wikipedia

   en.wikipedia.org/wiki/Signs_and_symptoms_of...

   Parkinson's Disease causes constipation and gastric dysmotility that is severe enough to endanger comfort and even health. [26] A factor in this is the appearance of Lewy bodies and Lewy neurites even before these affect the functioning of the substantia nigra in the neurons in the enteric nervous system that control gut functions. [27]

5. Type 2 diabetes drugs could lower dementia, Parkinson's ... - AOL

   www.aol.com/type-2-drugs-could-lower-133000670.html

   Researchers have found that people who take a type of type 2 diabetes drugs SGLT2 inhibitors have a significantly lower risk of dementia, overall, and of Alzheimer's disease and Parkinson's, in ...

6. Cotinine - Wikipedia

   en.wikipedia.org/wiki/Cotinine

   Cotinine has an in vivo half-life of approximately 20 hours, and is typically detectable for several days (up to one week) after the use of tobacco. The level of cotinine in the blood, saliva, and urine is proportionate to the amount of exposure to tobacco smoke, so it is a valuable indicator of tobacco smoke exposure, including secondary (passive) smoke. [14]

7. Parkinsonism - Wikipedia

   en.wikipedia.org/wiki/Parkinsonism

   Parkinsonism is a clinical syndrome characterized by the four motor symptoms found in Parkinson's disease: tremor, bradykinesia (slowed movements), rigidity, and postural instability. [ 1 ] [ 2 ] Parkinsonism gait problems can lead to falls and serious physical injuries.