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  2. Cirrhosis - Wikipedia

    en.wikipedia.org/wiki/Cirrhosis

    Person with cirrhosis and associated pain in the right upper region of the abdomen. Cirrhosis can take quite a long time to develop, and symptoms may be slow to emerge. [13] Some early symptoms include tiredness, weakness, loss of appetite, weight loss, and nausea. [13] Early signs may also include redness on the palms known as palmar erythema ...

  3. Primary sclerosing cholangitis - Wikipedia

    en.wikipedia.org/wiki/Primary_sclerosing_cholangitis

    Portal hypertension, a complication of cirrhosis, which can manifest with esophageal and parastomal varices [10] as well as hepatic encephalopathy (mental status alteration/disturbance caused by liver dysfunction and shunting of blood away from the scarred liver; such that ammonia detoxification is reduced with concomitant encephalopathy) or ...

  4. Primary biliary cholangitis - Wikipedia

    en.wikipedia.org/wiki/Primary_biliary_cholangitis

    Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune disease of the liver. [ 1 ] [ 2 ] [ 3 ] It results from a slow, progressive destruction of the small bile ducts of the liver, causing bile and other toxins to build up in the liver, a condition called cholestasis .

  5. Autoimmune hepatitis - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_hepatitis

    Liver cirrhosis can develop in about 7% to 40% of treated patients. People with the highest risk for progression to cirrhosis are those with incomplete response to treatment, treatment failure, and multiple relapses. Once cirrhosis develops, management of liver cirrhosis in autoimmune hepatitis is standard regardless of etiology.

  6. Chronic liver disease - Wikipedia

    en.wikipedia.org/wiki/Chronic_liver_disease

    Chronic liver disease takes several years to develop and the condition may not be recognised unless there is clinical awareness of subtle signs and investigation of abnormal liver function tests. Testing for chronic liver disease involves blood tests, imaging including ultrasound, and a biopsy of the liver. The liver biopsy is a simple ...

  7. Liver disease - Wikipedia

    en.wikipedia.org/wiki/Liver_disease

    [47] [48] Alcohol-related liver disease accounts for about 4.5% of liver-related deaths globally, underscoring the substantial burden of alcohol misuse. [49] Viral hepatitis, primarily hepatitis B and hepatitis C, remains a leading cause of liver cirrhosis and liver cancer worldwide, despite advances in antiviral therapies and vaccination ...

  8. Elevated transaminases - Wikipedia

    en.wikipedia.org/wiki/Elevated_transaminases

    Muscle sources of the enzymes, such as intense exercise, are unrelated to liver function and can markedly increase AST and ALT. [5] Cirrhosis of the liver or fulminant liver failure secondary to hepatitis commonly reach values for both ALT and AST in the >1000 U/L range; however, many people with liver disease have normal transaminases.

  9. Portal vein thrombosis - Wikipedia

    en.wikipedia.org/wiki/Portal_vein_thrombosis

    Anticoagulation for patients with cirrhosis who experience portal vein thrombosis is usually not advised unless they have chronic PVT 1) with thrombophilia, 2) with clot burden in the mesenteric veins, or 3) inadequate blood supply to the bowels. [3] In more severe instances, shunts or a liver transplant may be considered. If blood flow to the ...