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  2. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    Gabapentin at a low dose of 100 mg has a T max (time to peak levels) of approximately 1.7 hours, while the T max increases to 3 to 4 hours at higher doses. [86] Food does not significantly affect the T max of gabapentin and increases the C max and area-under-curve levels of gabapentin by approximately 10%. [94]

  3. Gabapentinoid - Wikipedia

    en.wikipedia.org/wiki/Gabapentinoid

    Gabapentin at a low dose of 100 mg has a T max (time to peak levels) of approximately 1.7 hours, while the T max increases to 3 to 4 hours at higher doses. [1] The T max of pregabalin is generally less than or equal to 1 hour at doses of 300 mg or less. [1]

  4. Clark's rule - Wikipedia

    en.wikipedia.org/wiki/Clark's_rule

    Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...

  5. Child-resistant packaging - Wikipedia

    en.wikipedia.org/wiki/Child-resistant_packaging

    A bottle of aspirin with a child-resistant cap bearing the instruction "push down & turn to open" Opening many C-R packages involves two dissimilar motions. Child-resistant packaging or CR packaging is special packaging used to reduce the risk of children ingesting hazardous materials. This is often accomplished by the use of a special safety cap.

  6. Gabapentin enacarbil - Wikipedia

    en.wikipedia.org/wiki/Gabapentin_enacarbil

    Gabapentin enacarbil (Horizant (ER) (U.S. Tooltip United States), Regnite (in Japan)) is an anticonvulsant and analgesic drug of the gabapentinoid class, and a prodrug to gabapentin. [1] It was designed for increased oral bioavailability over gabapentin, [ 2 ] [ 3 ] and human trials showed it to produce extended release of gabapentin with ...

  7. Pregabalin - Wikipedia

    en.wikipedia.org/wiki/Pregabalin

    [19] [29] Because of its chemical and pharmacological similarities to gabapentin, it is sometimes called a gabapentinoid drug. Specifically, pregabalin is ( S )-(+)-3-isobutyl-GABA. [ 116 ] [ 117 ] [ 118 ] Pregabalin also closely resembles the α-amino acids L -leucine and L -isoleucine , and this may be of greater relevance in relation to its ...

  8. Poison Prevention Packaging Act of 1970 - Wikipedia

    en.wikipedia.org/wiki/Poison_Prevention...

    Poison Prevention Packaging Act of 1970; Long title: An Act to amend the Federal Hazardous Substances Act to provide for child resistant packaging to protect children from serious personal injury or serious illness resulting from handling, using, or ingesting a hazardous substance, and for other purposes.

  9. Vigabatrin - Wikipedia

    en.wikipedia.org/wiki/Vigabatrin

    Vigabatrin reduced cholecystokinin tetrapeptide-induced symptoms of panic disorder, in addition to elevated cortisol and ACTH levels, in healthy volunteers. [12]Vigabatrin is also used to treat seizures in succinic semialdehyde dehydrogenase deficiency (SSADHD), which is an inborn GABA metabolism defect that causes intellectual disability, hypotonia, seizures, speech disturbance, and ataxia ...

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