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The 1918–1920 flu pandemic, also known as the Great Influenza epidemic or by the common misnomer Spanish flu, was an exceptionally deadly global influenza pandemic caused by the H1N1 subtype of the influenza A virus.
The 1918 flu pandemic, commonly referred to as the Spanish flu, was a category 5 influenza pandemic caused by an unusually severe and deadly Influenza A virus strain of subtype H1N1. The difference between the influenza mortality age-distributions of the 1918 epidemic and normal epidemics.
The 1918 influenza pandemic has been declared, according to Barry's text, as the 'deadliest plague in history'. The extensiveness of this declaration can be supported through the following statements: "the greatest medical holocaust in history" [2] and "the pandemic ranks with the plague of Justinian and the Black Death as one of the three most destructive human epidemics". [3]
On 18 January 2007, Kobasa et al. reported that infected monkeys (Macaca fascicularis) exhibited classic symptoms of the 1918 pandemic and died from a cytokine storm. [24] The sequences of the polymerase proteins (PA, PB1, and PB2) of the 1918 virus and subsequent human viruses differ by only 10 amino acids from the avian influenza viruses.
The 1918–1920 flu pandemic is commonly referred to as the Spanish flu, and caused millions of deaths worldwide. To maintain morale, wartime censors minimized early reports of illness and mortality in Germany , the United Kingdom , France , and the United States .
This is a timeline of influenza, briefly describing major events such as outbreaks, epidemics, pandemics, discoveries and developments of vaccines.In addition to specific year/period-related events, there is the seasonal flu that kills between 250,000 and 500,000 people every year and has claimed between 340 million and 1 billion human lives throughout history.
From 1918 to 1920, the Spanish flu pandemic became the most devastating influenza pandemic and one of the deadliest pandemics in history. The pandemic, caused by an H1N1 strain of influenza A, [ 80 ] likely began in the United States before spreading worldwide via soldiers during and after the First World War .
The Anti-Mask League was an organization formed in San Francisco, California to protest an ordinance which required people in that city to wear masks during the 1918 influenza pandemic. The ordinance it protested lasted less than one month before being repealed.