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Photo 51 is an X-ray based fiber diffraction image of a paracrystalline gel composed of DNA fiber [1] taken by Raymond Gosling, [2] [3] a postgraduate student working under the supervision of Maurice Wilkins and Rosalind Franklin at King's College London, while working in Sir John Randall's group.
Other forms of elastic X-ray scattering besides single-crystal diffraction include powder diffraction, small-angle X-ray scattering and several types of X-ray fiber diffraction, which was used by Rosalind Franklin in determining the double-helix structure of DNA. In general, single-crystal X-ray diffraction offers more structural information ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 12 February 2025. British X-ray crystallographer (1920–1958) This article is about the chemist. For the Mars rover named after her, see Rosalind Franklin (rover). Rosalind Franklin Franklin with a microscope in 1955 Born Rosalind Elsie Franklin (1920-07-25) 25 July 1920 Notting Hill, London, England ...
Wilkins ordered a new X-ray tube and a new microcamera. He also suggested to Randall that the soon-to-be-appointed Rosalind Franklin should be reassigned from work on protein solutions to join the DNA effort. [28] By the summer of 1950 Randall had arranged for a three-year research fellowship that would fund Rosalind Franklin in his laboratory.
The double-helix model of DNA structure was first published in the journal Nature by James Watson and Francis Crick in 1953, [6] (X,Y,Z coordinates in 1954 [7]) based on the work of Rosalind Franklin and her student Raymond Gosling, who took the crucial X-ray diffraction image of DNA labeled as "Photo 51", [8] [9] and Maurice Wilkins, Alexander Stokes, and Herbert Wilson, [10] and base-pairing ...
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They produced the first X-ray diffraction photographs of the "wet form B" (B-DNA) paracrystalline arrays of highly hydrated DNA. In 1952 Gosling made the best X-ray diffraction image of DNA known as Photo 51. [8] This piece of evidence helped Francis Crick and James D. Watson to decipher the correct chemical structure.
Using "Photo 51" (the X-ray diffraction results of Rosalind Franklin and her graduate student Raymond Gosling of King's College London, given to them by Gosling and Franklin's colleague Wilkins), Watson and Crick together developed a model for a helical structure of DNA, which they published in 1953. [36]
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