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Complications related to extravasation are possible with any medication. Since vesicants are blistering agents, extravasation may lead to irreversible tissue injury. Extravasation is particularly serious during chemotherapy, since chemotherapy medications are highly toxic.
Extravasation of irrigation fluid is the unintended migration of irrigation fluid (e.g., saline) introduced into a human body.This may occur in several types of endoscopic surgery, such as minimally invasive orthopedic surgery, i.e., arthroscopy, TURP (trans-urethral resection of the prostate), and TCRE (trans-cervical resection of the endometrium).
An injury to the urethra leaving Buck's fascia intact results in a collection of urine (extravasation) limited to the penis, deep to Buck's fascia. If the injury to the bulb of the penis results in urethral injury accompanying a tear of Buck's fascia, then extravasated blood and urine accumulates in the superficial perineal space, passing into the penis (outer to Buck's fascia) as well as the ...
When anthracyclines are given intravenously, it may result in accidental extravasation at injection sites. It is estimated that the extravasation incidence ranges from 0.1% to 6%. [ 38 ] Extravasation causes serious complications to surrounding tissues with the symptoms of tissue necrosis and skin ulceration. [ 38 ]
A blister agent (or vesicant), is a chemical compound that causes severe skin, eye and mucosal pain and irritation. They are named for their ability to cause severe chemical burns , resulting in painful water blisters on the bodies of those affected.
Neutrophils extravasate from blood vessels to the site of tissue injury or infection during the innate immune response.. In immunology, leukocyte extravasation (also commonly known as leukocyte adhesion cascade or diapedesis – the passage of cells through the intact vessel wall) is the movement of leukocytes (white blood cells) out of the circulatory system (extravasation) and towards the ...
This series came from a determination to understand why, and to explore how their way back from war can be smoothed. Moral injury is a relatively new concept that seems to describe what many feel: a sense that their fundamental understanding of right and wrong has been violated, and the grief, numbness or guilt that often ensues.
A mixed inflammatory cell population surrounding the postcapillary venules of the superficial dermis. The infiltrate consists of neutrophils with nuclear dust (dashed arrows) and shows high affinity for the vessels. Features of vascular injury are shown including fibrinoid necrosis (asterisks) and erythrocyte extravasation (solid arrows). [11]