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1654 13205 Ensembl ENSG00000215301 ENSMUSG00000000787 UniProt O00571 Q62167 RefSeq (mRNA) NM_001193416 NM_001193417 NM_001356 NM_024005 NM_001363819 NM_010028 NM_008015 RefSeq (protein) NP_001180345 NP_001180346 NP_001347 NP_001350748 NP_034158 Location (UCSC) Chr X: 41.33 – 41.36 Mb Chr X: 13.15 – 13.16 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse ATP-dependent RNA helicase ...
22427 Ensembl ENSG00000165392 ENSMUSG00000031583 UniProt Q14191 O09053 RefSeq (mRNA) NM_000553 NM_001122822 NM_011721 RefSeq (protein) NP_000544 NP_001116294 NP_035851 Location (UCSC) Chr 8: 31.03 – 31.18 Mb Chr 8: 33.72 – 33.88 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Werner syndrome ATP-dependent helicase, also known as DNA helicase, RecQ-like type 3, is an enzyme that ...
Helicases are often used to separate strands of a DNA double helix or a self-annealed RNA molecule using the energy from ATP hydrolysis, a process characterized by the breaking of hydrogen bonds between annealed nucleotide bases.
RIG-I domain architecture. (A) Schematic representation of full-length RIG-I. (B) X-ray crystal structure of RNA-bound RIG-I ( ), excluding the CARD domains.The RLR receptors are members of the DEAD-box (SF2) helicase family (despite containing a DExD/H motif, rather than the DEAD motif characteristic of the family) and share a common domain architecture.
A representation of the structures of the replisome during DNA replication. The replisome is a complex molecular machine that carries out replication of DNA.The replisome first unwinds double stranded DNA into two single strands.
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Eukaryotic DNA replication. Eukaryotic DNA replication is a conserved mechanism that restricts DNA replication to once per cell cycle. Eukaryotic DNA replication of chromosomal DNA is central for the duplication of a cell and is necessary for the maintenance of the eukaryotic genome.
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