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  2. Folate deficiency - Wikipedia

    en.wikipedia.org/wiki/Folate_deficiency

    Signs of folate deficiency anemia most of the time are subtle. [4] Anemia (macrocytic, megaloblastic anemia) can be a sign of advanced folate deficiency in adults. [1] Folate deficiency anemia may result in feeling tired, weakness, changes to the color of the skin or hair, open sores on the mouth, shortness of breath, palpitations, lightheadedness, cold hands and feet, headaches, easy bleeding ...

  3. Folate - Wikipedia

    en.wikipedia.org/wiki/Folate

    PCFT binds to both reduced folates and folic acid. A secondary folate transporter is the reduced folate carrier (RFC), coded for by the SLC19A1 gene. It operates optimally at pH 7.4 in the ileum portion of the small intestine. It has a low affinity for folic acid. Production of the receptor proteins is increased in times of folate deficiency. [78]

  4. Cerebral folate deficiency - Wikipedia

    en.wikipedia.org/wiki/Cerebral_folate_deficiency

    In children with cerebral folate deficiency, the cerebrospinal fluid shows low levels of 5MTHF, and a loss of white matter in the brain (leukodystrophy) may occur. As a result of the decreased levels of 5MTHF, the child experiences low levels of Vitamin B folate. [12] There is inability for the 5MTHF to be transported across the blood-brain ...

  5. Hereditary folate malabsorption - Wikipedia

    en.wikipedia.org/wiki/Hereditary_folate_mal...

    The CSF folate level is usually undetectable at the time of diagnosis. Even when the blood folate level is corrected, or far above normal, the CSF folate level remains low, consistent with impaired transport across the choroid plexus. The normal CSF folate level in children over the first three years of life is in the 75 to 150 nM range.

  6. Victor Herbert (hematologist) - Wikipedia

    en.wikipedia.org/wiki/Victor_Herbert_(Hematologist)

    Herbert, V. & Zalusky, R. (1962) Interrelations of vitamin B-12 and folic acid metabolism: folic acid clearance studies. J. Clin. Investig. 41:1263-1276. 3. Herbert, V. (1962) Experimental nutritional folate deficiency in man. Transactions of the Association of American Physicians 75: 307-320.

  7. Neural tube defect - Wikipedia

    en.wikipedia.org/wiki/Neural_tube_defect

    [28] [29] A diet rich in natural folate (350 μg/d) can show as much increase in plasma folate as taking low levels of folic acid (250 μg/d) in individuals [30] However a comparison of general population outcomes across many countries with different approaches to increasing folate consumption has found that only general food fortification with ...

  8. Folic acid may help lower risk of suicide attempts, study ...

    www.aol.com/lifestyle/folic-acid-may-help-lower...

    But if further studies confirm folic acid — which is inexpensive and widely available — as a suicide prevention tool, “it will be significant for the patients that have low folate levels ...

  9. Anemia in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Anemia_in_pregnancy

    Vitamin B12: Women who consume strictly vegan diets are advised to take Vitamin B12 supplements; this helps prevent anemia due to low Vitamin B12 levels. [29] Folic Acid: Folic acid supplement recommended for women with history of documented folate deficiency. Folic acid supplementation also recommended for prevention of neural tube defects in ...

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