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Smallpox was an infectious disease caused by variola virus (often called smallpox virus), which belongs to the genus Orthopoxvirus. [7] [11] The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, [10] making smallpox the only human disease to have been eradicated to date.
Smallpox was a dangerous disease caused by the variola major virus. The most common type of smallpox, ordinary, historically has devastated populations with a 30% death rate. The smallpox virus is transmittable through bodily fluids and materials contaminated with infected materials.
Smallpox has had a major impact on world history, not least because indigenous populations of regions where smallpox was non-native, such as the Americas and Australia, were rapidly and greatly reduced by smallpox (along with other introduced diseases) during periods of initial foreign contact, which helped pave the way for conquest and ...
Diseases associated with this genus include smallpox, cowpox, horsepox, camelpox, and mpox. [ 1 ] [ 2 ] The most widely known member of the genus is Variola virus , which causes smallpox. It was eradicated globally by 1977, through the use of Vaccinia virus as a vaccine .
Smallpox is the first disease, and so far the only infectious disease of humans, to be eradicated by deliberate intervention. [6] It became the first disease for which there was an effective vaccine in 1798 when Edward Jenner showed the protective effect of inoculation (vaccination) of humans with material from cowpox lesions. [10]
The Centers for Disease Control reports that there have been more than 22,400 cases across 79 countries around the world. Almost 99% of monkeypox cases from the current outbreak have been reported ...
The FBI and the Center for Disease Control and Prevention are investigating “questionable vials” labeled "smallpox" and found in a freezer last night at a Merck facility outside Philadelphia.
The last cases of smallpox occurred in an outbreak of two cases, one of which was fatal, in Birmingham, United Kingdom, in 1978. A medical photographer, Janet Parker, contracted the disease at the University of Birmingham Medical School and died on September 11, 1978. [3]