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A hypertrophic scar is a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids. [1] Like keloids, they form most often at the sites of pimples, body piercings, cuts and burns. They often contain nerves and blood vessels.
Severe cutaneous adverse reactions (SCARs) are a group of potentially lethal adverse drug reactions that involve the skin and mucous membranes of various body openings such as the eyes, ears, and inside the nose, mouth, and lips. In more severe cases, SCARs also involves serious damage to internal organs. SCARs includes five syndromes:
Hyperkeratosis is thickening of the stratum corneum (the outermost layer of the epidermis, or skin), often associated with the presence of an abnormal quantity of keratin, [1] and is usually accompanied by an increase in the granular layer. As the corneum layer normally varies greatly in thickness in different sites, some experience is needed ...
In severe cases, it can affect movement of skin. In the United States, keloid scars are seen 15 times more frequently in people of sub-Saharan African descent than in people of European descent. [3] There is a higher tendency to develop a keloid among those with a family history of keloids and people between the ages of 10 and 30 years. [4]
Erythroderma is an inflammatory skin disease with redness and scaling that affects nearly the entire cutaneous surface. [ 1 ] [ 2 ] This term applies when 90% or more of the skin is affected. In ICD-10 , a distinction is made between "exfoliative dermatitis" at L26, and "erythroderma" at L53.9.
Scar sarcoid (also known as "Sarcoidosis in scars") is a cutaneous condition characterized by infiltration and elevation of tattoos and old flat scars due to sarcoidosis. [2]: 710 Mucosal sarcoidosis is a cutaneous condition characterized by pinhead-sized papules that may be grouped and fused together to form a flat plaque. [2]: 711
-The plaques are characterized histologically by hyperkeratosis which is a thickening of the outer layer of skin. Hyperkeratosis is often associated with an abnormal amount of keratin production. Also characteristic is moderate acanthosis a thickening of the stratum spinosum with elongation of rete ridges. [citation needed]
Marjolin's ulcer refers to an aggressive ulcerating squamous cell carcinoma presenting in an area of previously traumatized, [1] chronically inflamed, [2] or scarred skin. [3]: 737 [4] They are commonly present in the context of chronic wounds including burn injuries, varicose veins, venous ulcers, [5] ulcers from osteomyelitis, [6] and post radiotherapy scars.