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[2] [1] Radiation proctitis most commonly occurs after pelvic radiation treatment for cancers such as cervical cancer, prostate cancer, bladder cancer, and rectal cancer. RAVE and chronic radiation proctopathy involves the lower intestine , primarily the sigmoid colon and the rectum, and was previously called chronic radiation proctitis, pelvic ...
A 2024 systematic review of the literature found that chemoradiation with 5-FU and mitomycin C, as used in the Nigro Protocol, improves outcomes like colostomy-free survival in anal cancer patients compared to alternatives like cisplatin. However, it can lead to more severe side effects, especially blood-related toxicity. [7]
Constipation is more concerning when there is weight loss or anemia, blood is present in the stool, there is a history of inflammatory bowel disease or colon cancer in a person's family, or it is of new onset in someone who is older. [12] Treatment of constipation depends on the underlying cause and the duration that it has been present. [4]
Radiation-induced FI may involve the anal canal as well as the rectum, when proctitis, anal fistula formation, and diminished function of internal and external sphincter occur. [2] Irradiation may occur during radiotherapy , e.g. for prostate cancer .
Dose fractionation effects are utilised in the treatment of cancer with radiation therapy. When the total dose of radiation is divided into several, smaller doses over a period of several days, there are fewer toxic effects on healthy cells. This maximizes the effect of radiation on cancer and minimizes the negative side effects. A typical ...
People taking laxatives who experience sudden weight loss, blood in their stool or constipation lasting more than three months should see a doctor, said Dr. Satish Rao, a professor of medicine at ...
Side effects of nausea and constipation are rarely severe enough to warrant stopping of treatment. [38] Sedation and cognitive impairment usually occur with the initial dose or a significant increase in dosage of a strong opioid, but improve after a week or two of consistent dosage.
Randy Moss is undergoing treatment for bile duct cancer. The legendary NFL wide receiver-turned-broadcaster announced his diagnosis in an Instagram live video on Friday afternoon . "Your boy is a ...