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Major factors influencing cardiac output – heart rate and stroke volume, both of which are variable. [1]In cardiac physiology, cardiac output (CO), also known as heart output and often denoted by the symbols , ˙, or ˙, [2] is the volumetric flow rate of the heart's pumping output: that is, the volume of blood being pumped by a single ventricle of the heart, per unit time (usually measured ...
The flow profiles was first derived by John R. Womersley (1907–1958) in his work with blood flow in arteries. [1] The cardiovascular system of chordate animals is a very good example where pulsatile flow is found, but pulsatile flow is also observed in engines and hydraulic systems, as a result of rotating mechanisms pumping the fluid.
For this reason, the blood flow velocity is the fastest in the middle of the vessel and slowest at the vessel wall. In most cases, the mean velocity is used. [18] There are many ways to measure blood flow velocity, like videocapillary microscoping with frame-to-frame analysis, or laser Doppler anemometry. [19]
Pulse wave velocity (PWV) is the velocity at which the blood pressure pulse propagates through the circulatory system, usually an artery or a combined length of arteries. [1] PWV is used clinically as a measure of arterial stiffness and can be readily measured non-invasively in humans, with measurement of carotid to femoral PWV (cfPWV) being ...
Venous return (VR) is the flow of blood back to the heart. Under steady-state conditions, venous return must equal cardiac output (Q), when averaged over time because the cardiovascular system is essentially a closed loop. Otherwise, blood would accumulate in either the systemic or pulmonary circulations.
Velocity Time Integral is a clinical Doppler ultrasound measurement of blood flow, equivalent to the area under the velocity time curve. The product of VTI (cm/stroke) and the cross sectional area of a valve (cm2) yields a stroke volume (cm3/stroke), which can be used to calculate cardiac output.
It is a dimensionless expression of the pulsatile flow frequency in relation to viscous effects. It is named after John R. Womersley (1907–1958) for his work with blood flow in arteries. [1] The Womersley number is important in keeping dynamic similarity when scaling an experiment. An example of this is scaling up the vascular system for ...
As the blood moves into the aortic arch, the area with the highest velocity tends to be on the inner wall. Helical flow within the ascending aorta and aortic arch help to reduce flow stagnation and increase oxygen transport. [4] As the blood moves into the descending aorta, rotations in the flow are less present.