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Ketone bodies that commonly appear in the urine when fats are burned for energy are acetoacetate and beta-hydroxybutyric acid. Acetone is also produced and is expired by the lungs. [ 1 ] Normally, the urine should not contain a noticeable concentration of ketones to give a positive reading.
The presence of detectable levels of ketones in the urine is called ketonuria. Ketones occur in three forms in the body: beta-hydroxybutyrate (BHB), acetone and acetoacetate. Test strips use sodium nitroprusside to detect acetoacetate, and those with a glycine additive can detect acetone; however, none detect BHB. The reaction of ketones with ...
In organic chemistry, a ketone / ˈ k iː t oʊ n / is an organic compound with the structure R−C(=O)−R', where R and R' can be a variety of carbon-containing substituents. Ketones contain a carbonyl group −C(=O)− (a carbon-oxygen double bond C=O). The simplest ketone is acetone (where R and R' is methyl), with the formula (CH 3) 2 CO ...
The term ketones or ketone bodies in reality refers to three intermediate products in the metabolism of fatty acids; acetone, acetoacetic acid and beta-hydroxybutyric acid. Elevated concentrations of ketones are not generally found in urine, as all these substances are completely metabolized, producing energy, carbon dioxide and water.
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Test for ketonuria using Bayer Ketostix reagent strips. Urine testing is the most common method of testing for ketones. Urine test strips utilize a nitroprusside reaction with acetoacetate to give a semi-quantitative measure based on color change of the strip. Although beta-hydroxybutyrate is the predominant circulating ketone, urine test ...
Acetone (2-propanone or dimethyl ketone) is an organic compound with the formula (CH 3) 2 CO. [22] It is the simplest and smallest ketone ( >C=O ). It is a colorless, highly volatile , and flammable liquid with a characteristic pungent odour, very reminiscent of the smell of pear drops .
The concentration of ketone bodies in blood is maintained around 1 mg/dL. Their excretion in urine is very low and undetectable by routine urine tests (Rothera's test). [18] When the rate of synthesis of ketone bodies exceeds the rate of utilization, their concentration in blood increases; this is known as ketonemia.
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