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The blastocyst stage occurs between 5 and 9 days after conception. During embryonic development, after fertilization (approximately 5–6 days in the human), the cells of the morula begin to undergo cell differentiation, and the morula changes into the blastocyst by pumping fluid to grow a lumen.
The germinal stage refers to the time from fertilization through the development of the early embryo until implantation is completed in the uterus. The germinal stage takes around 10 days. [1] During this stage, the zygote divides in a process called cleavage. A blastocyst is then formed and implants in the uterus.
A. Morula and B. cross section of a blastula displaying the blastocoel and blastoderm of early animal embryonic development. Blastulation is the stage in early animal embryonic development that produces the blastula. In mammalian development, the blastula develops into the blastocyst with a differentiated inner cell mass and an outer trophectoderm.
The development of a zygote into a multicellular embryo proceeds through a series of recognizable stages, often divided into cleavage, blastula, gastrulation, and organogenesis. [ 6 ] Cleavage is the period of rapid mitotic cell divisions that occur after fertilization.
It is the mass of cells inside the blastocyst that will eventually give rise to the definitive structures of the fetus. The inner cell mass forms in the earliest stages of embryonic development, before implantation into the endometrium of the uterus. [1] The ICM is entirely surrounded by the single layer of trophoblast cells of the trophectoderm.
Cavitation is a process in early embryonic development that follows cleavage. Cavitation is the formation of the blastocoel, a fluid-filled cavity that defines the blastula, or in mammals the blastocyst. [1] After fertilization, cell division of the zygote occurs which results in the formation of a solid ball of cells (blastomeres) called the ...
Once the blastocyst is formed, it undergoes implantation into the endometrium. [4] During implantation the blastocyst, which contains the inner cell mass, undergoes cellular differentiation into the two layers of the bilaminar embryonic disc. One of which is the epiblast, also known as the primitive ectoderm.
In human embryonic development at the eight-cell stage, having undergone three cleavages the embryo starts to change shape as it develops into a morula and then a blastocyst. At the eight-cell stage the blastomeres are initially round, and only loosely adhered.