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Process analytical technology (PAT) has been defined by the United States Food and Drug Administration (FDA) as a mechanism to design, analyze, and control pharmaceutical manufacturing processes through the measurement of critical process parameters (CPP) which affect the critical quality attributes (CQA).
The material cost of a chemical process is the sum of the costs of all raw materials, intermediates, reagents, solvents, and catalysts procured from external vendors. Material costs may influence the selection of one synthetic route over another or the decision to outsource production of an intermediate.
Material flow analysis (MFA), also referred to as substance flow analysis (SFA), is an analytical method to quantify flows and stocks of materials or substances in a well-defined system. MFA is an important tool to study the bio-physical aspects of human activity on different spatial and temporal scales.
Material flow accounts provide information on the material inputs into, the changes in material stock within, and the material outputs in the form of exports to other economies or discharges to the environment of an economy. Material flow accounting can be used in national planning, especially for scarce resources, and also allows for forecasting.
These measurements may be for quality control of raw material or final product, environmental compliance, safety, energy reduction or process control purposes. Vapour applications may include hydrocarbon feed stocks and intermediates (ethylene, ethane, propylene, etc.), natural gas streams, liquefied petroleum gas (LPG) streams, hydrogen and ...
A raw material going into a chemical process or plant as input to be converted into a product is commonly called a feedstock, or simply feed. In addition to feedstocks for the plant, as a whole, an input stream of material to be processed in a particular unit can similarly be considered feed for that unit.
Pharmaceutical manufacturing is the process of industrial-scale synthesis of pharmaceutical drugs as part of the pharmaceutical industry. The process of drug manufacturing can be broken down into a series of unit operations , such as milling , granulation , coating , tablet pressing , and others.
A raw material, also known as a feedstock, unprocessed material, or primary commodity, is a basic material that is used to produce goods, finished goods, energy, or intermediate materials that are feedstock for future finished products. As feedstock, the term connotes these materials are bottleneck assets and are required to produce other products.