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Neonatal lupus erythematosus is an autoimmune disease in an infant born to a mother with anti-Ro/SSA and with or without anti-La/SSB antibodies. [ 1 ] [ 2 ] The disease most commonly presents with a rash resembling subacute cutaneous lupus erythematosus and can have systemic abnormalities such as complete heart block or hepatosplenomegaly . [ 3 ]
Neonatal lupus is the occurrence of lupus symptoms in an infant born from a mother with lupus, most commonly presenting with a rash resembling discoid lupus erythematosus, and sometimes with systemic abnormalities such as heart block or hepatosplenomegaly. [9] Neonatal lupus is usually benign and self-limited. [9]
Lupus and pregnancy confers an increased rate of foetal death in utero and spontaneous abortion (miscarriage), as well as of neonatal lupus. [37] Thyroid disease in pregnancy can, if uncorrected, cause adverse effects on foetal and maternal well-being. [38]
Maternal physiological changes in pregnancy are the adaptations that take place during pregnancy that enable the accommodation of the developing embryo and fetus. These are normal physiological adaptations that cause changes in behavior , the functioning of the heart , blood vessels , and blood , metabolism including increases in blood sugar ...
The Maternal and Child Health Handbook was originally developed in Japan. However, in the 1980s, an Indonesian doctor who was visiting Japan through a training program of the semi-governmental corporation of Japan International Cooperation Agency (JICA) noticed its effectiveness in contributing to the health of mothers and children and decided to promote it in his own country. [14]
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Mother and child health. Both maternal and child health are interdependent and substantially contributing to high burden of mortality worldwide. Every year, 289 000 women die due to complications in pregnancy and childbirth, and 6.6 million children below 5 years of age die of complications in the newborn period and of common childhood diseases. [1]
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