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  2. HER2 - Wikipedia

    en.wikipedia.org/wiki/HER2

    HER2 is the target of the monoclonal antibody trastuzumab (marketed as Herceptin). Trastuzumab is effective only in cancers where HER2 is over-expressed. One year of trastuzumab therapy is recommended for all patients with HER2-positive breast cancer who are also receiving chemotherapy. [33] Twelve months of trastuzumab therapy is optimal.

  3. Breast cancer classification - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer_classification

    Trastuzumab deruxtecan is the first approved therapy by the US Food and Drug Administration (FDA) targeted to people with the HER2-low breast cancer subtype. [4] DNA-based classification. Understanding the specific details of a particular breast cancer may include looking at the cancer cell DNA or RNA by several different laboratory approaches ...

  4. Breast cancer - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer

    This is an accepted version of this page This is the latest accepted revision, reviewed on 30 December 2024. There is 1 pending revision awaiting review. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted ...

  5. Elle Macpherson explains why a holistic approach to breast ...

    www.aol.com/news/elle-macpherson-explains-why...

    Model Elle Macpherson was diagnosed with breast cancer ... "the Body" said she had a lumpectomy after being diagnosed with the form of breast cancer known in the medical field as HER2 positive ...

  6. Elle Macpherson Defends Decision to Refuse Chemotherapy ... - AOL

    www.aol.com/lifestyle/elle-macpherson-defends...

    The supermodel explained that a doctor called her after she had a lumpectomy and told her it was HER2 positive estrogen receptive intraductal carcinoma, which is a type of breast cancer, per the ...

  7. What is stage I triple-positive breast cancer? - AOL

    www.aol.com/lifestyle/office-star-jenna-fischer...

    When a tumor is “triple positive,” that means that its growth is fueled by both estrogen and progesterone hormones, as well as a protein called human epidermal growth factor receptor 2 (HER2 ...

  8. Breast cancer management - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer_management

    Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.

  9. Ai Detects Woman’s Breast Cancer After Routine Screening Missed It: 'Deeply Grateful' ... which acts like a smart missile targeting HER2-positive cancers. Another is repotrectinib, which works ...

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