Search results
Results from the WOW.Com Content Network
A transcriptional activator is a protein (transcription factor) that increases transcription of a gene or set of genes. [1] Activators are considered to have positive control over gene expression, as they function to promote gene transcription and, in some cases, are required for the transcription of genes to occur.
The Ac Activator element is autonomous, whereas the Ds Dissociation element requires an Activator element to transpose. [1] Ac was initially discovered as enabling a Ds element to break chromosomes. Both Ac and Ds can also insert into genes, causing mutants that may revert to normal on excision of the element. [2]
The VP64-p65-Rta, or VPR, dCas9 activator was created by modifying an existing dCas9 activator, in which a Vp64 transcriptional activator is joined to the C terminus of dCas9. [1] In the dCas9-VPR protein, the transcription factors p65 and Rta are added to the C terminus of dCas9-Vp64.
PGC-1α is a transcriptional coactivator that regulates the genes involved in energy metabolism. It is the master regulator of mitochondrial biogenesis . [ 6 ] [ 7 ] [ 8 ] This protein interacts with the nuclear receptor PPAR-γ , which permits the interaction of this protein with multiple transcription factors .
Steroid receptor RNA activator 1 also known as steroid receptor RNA activator protein (SRAP) is a protein that in humans is encoded by the SRA1 gene. [ 5 ] [ 6 ] The mRNA transcribed from the SRA1 gene is a component of the ribonucleoprotein complex containing NCOA1 .
For premium support please call: 800-290-4726 more ways to reach us
Tetracycline-controlled transcriptional activation is a method of inducible gene expression where transcription is reversibly turned on or off in the presence of the antibiotic tetracycline or one of its derivatives (e.g. doxycycline).
The FDIC is an independent government agency charged with maintaining stability and public confidence in the U.S. financial system and providing insurance on consumer deposit accounts.