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A bronchial challenge test is a medical test used to assist in the diagnosis of asthma. [1] The patient breathes in nebulized methacholine or histamine. Thus the test may also be called a methacholine challenge test or histamine challenge test respectively. Both drugs provoke bronchoconstriction, or narrowing of the airways.
The fraction of exhaled NO (FE NO) is a promising biomarker for the diagnosis, follow-up and as a guide to therapy in adults and children with asthma. The breath test has recently become available in many well-equipped hospitals in developed countries, although its exact role remains unclear.
Bear in mind, however, that this number does not apply to children, and that it can differ depending on the patient's native result; small patient's with pulmonary fibrosis, restrictive lung disease etc. will have a measurably lower FEV1 than healthy average-sized adults. This can give a false positive result of the test.
Due to the need for patient cooperation and an ability to understand and follow instructions, spirometry can typically only be done in cooperative children when they at least 5 years old [3] [4] or adults without physical or mental impairment preventing effective diagnostic results.
Asthma phenotyping and endotyping has emerged as a novel approach to asthma classification inspired by precision medicine which separates the clinical presentations of asthma, or asthma phenotypes, from their underlying causes, or asthma endotypes. The best-supported endotypic distinction is the type 2-high/type 2-low distinction.
It is classically reduced in obstructive lung disorders such as asthma. Due to the wide range of 'normal' values and the high degree of variability, peak flow is not the recommended test to identify asthma. However, it can be useful in some circumstances. A small portion of people with asthma may benefit from regular peak flow monitoring. When ...
Colorado head coach Deion Sanders issued a warning to NFL teams Friday − don’t draft Heisman Trophy winner Travis Hunter if you won’t let him play both ways.. Sanders said this on "The Rich ...
The Buteyko method emphasizes the role of carbon dioxide and hyperventilation in respiratory diseases as well as overall health. It is known that hyperventilation can lead to low carbon dioxide levels in the blood (or hypocapnea), which can subsequently lead to disturbances of the acid-base balance in the blood and lower tissue oxygen levels.