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Rather, the relationship of a gene symbol to the gene name is functionally the relationship of a nickname to a formal name (both are complete identifiers)—it is not the relationship of an acronym to its expansion. In fact, many official gene symbol–gene name pairs do not even share their initial-letter sequences (although some do).
Full gene names, and especially gene abbreviations and symbols, are often not specific to a single gene. A marked example is CAP which can refer to any of 6 different genes (BRD4 Archived 2013-10-27 at the Wayback Machine, CAP1 Archived 2013-11-02 at the Wayback Machine, HACD1 Archived 2013-10-07 at the Wayback Machine, LNPEP Archived 2012-09-13 at the Wayback Machine, SERPINB6 Archived 2013 ...
To be processed, a valid Gene ID must exist for the specific gene, or the Gene staff must have assigned an overall Gene ID to the species. The latter case is implemented via records in Gene with the symbol NEWENTRY. Once the Gene ID is identified, only three types of information are required to complete a submission:
Users can select various types of identifiers such as CCDS ID, gene ID, gene symbol, nucleotide ID and protein ID to search for specific CCDS information. [1] The CCDS reports (Figure 1) are presented in a table format, providing links to specific resources, such as a history report, Entrez Gene [ 10 ] or re-query the CCDS data set.
[4] [15] Symbol Sources include HGNC (HUGO Gene Nomenclature Committee), EntrezGene (gene-centered information at NCBI), Ensembl, GeneCards RNA genes, CroW21 and so on. [5] Moreover, the user can choose to search for All GeneCards or Within Gene Subset, which would be more specific and with priority.
Gene nomenclature was established by the HUGO Gene Nomenclature Committee (HGNC), a committee of the Human Genome Organisation, for each known human gene in the form of an approved gene name and symbol (short-form abbreviation), which can be accessed through a database maintained by HGNC. Symbols are chosen to be unique, and each gene has only ...
While there is much commonality, different parts of the tree of life use slightly different genetic codes. [1] When translating from genome to protein, the use of the correct genetic code is essential.
The service allows researchers to submit candidate genes to a database and match based on a shared gene of interest. Researchers, healthcare providers or patients can create an account using their email, name and address. Upon doing this, they can post a gene by gene symbol, Entrez ID or Ensembl gene ID.