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Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [5] Those affected often have a gradual onset. [ 5 ] The most common initial symptoms are feeling tired and weak. [ 4 ]
Pernicious anemia is the most common cause of vitamin B 12 deficiency anemia in adults, which results from malabsorption of vitamin B 12 due to a lack or loss of intrinsic factor. [ 2 ] [ 8 ] There are relatively few studies which have assessed the impact of haematological measures in response to B 12 supplementation.
[6] [15] [26] Vitamin B 12 deficiency can also cause symptoms of mania and psychosis. [27] [28] Among other problems, weakened immunity, reduced fertility and interruption of blood circulation in women may occur. [29] The main type of vitamin B12 deficiency anemia is pernicious anemia, [30] characterized by a triad of symptoms:
Pernicious anemia. As mentioned above, B12 needs to be combined with a protein called intrinsic factor in the stomach before it is absorbed. ... “A B12 deficiency can cause physical and ...
Your body can end up making fewer red blood cells if you have a vitamin B12 deficiency, leading to a specific type of anemia, according to Johns Hopkins Medicine. Assists with DNA synthesis .
Nutritional anemia can be caused by a lack of iron, protein, vitamin B12, and other vitamins and minerals that are needed for the formation of hemoglobin. However, Iron deficiency anemia is the most common nutritional disorder. [7] Signs of anemia include cyanosis, jaundice, and easy bruising. [7]
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