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  2. Opioid overdose - Wikipedia

    en.wikipedia.org/wiki/Opioid_overdose

    Naloxone is then recommended to those who cannot reverse the opioid's effects through breathing. [10] [3] Giving naloxone via nasal administration or as an injection into a muscle has shown to be equally effective. [11] Other efforts to prevent deaths from overdose include increasing access to naloxone and treatment for opioid dependence. [1] [12]

  3. Opioid - Wikipedia

    en.wikipedia.org/wiki/Opioid

    Opioid antagonists remain the standard treatment for respiratory depression following opioid overdose, with naloxone being by far the most commonly used, although the longer acting antagonist nalmefene may be used for treating overdoses of long-acting opioids such as methadone, and diprenorphine is used for reversing the effects of extremely ...

  4. Fentanyl - Wikipedia

    en.wikipedia.org/wiki/Fentanyl

    Pharmaceutical fentanyl's adverse effects are identical to those of other opioids and narcotics, [17] including addiction, confusion, respiratory depression (which, if extensive and untreated, may lead to respiratory arrest), drowsiness, nausea, visual disturbances, dyskinesia, hallucinations, delirium, a subset of the latter known as "narcotic ...

  5. Narcotic - Wikipedia

    en.wikipedia.org/wiki/Narcotic

    Endogenous opioids (enkephalins, dynorphin, endorphin) do not bind specifically to any particular opioid receptor. Receptor binding of the opioid causes a cascade leading to the channel opening and hyperpolarization of the neuron. The opioid receptors have the following channel types: mu, K + channel; l delta, K + channel; kappa, Ca 2+ channel ...

  6. Prescription drug addiction - Wikipedia

    en.wikipedia.org/wiki/Prescription_Drug_Addiction

    When a chronic prescription drug user suddenly ceases the use of an addictive drug, the person may experience unpleasant withdrawal symptoms depending on the drug type. [24] A constant opioid user may experience withdrawal symptoms such as nausea and diarrhea. [47] Detoxification is a procedure which treats addicts in withdrawal with low doses ...

  7. A fentanyl antidote is saving lives. But it isn’t ending the ...

    www.aol.com/news/fentanyl-antidote-saving-lives...

    “I love getting high,” says James “Sleaze” Morgan. But the antidote to fentanyl is a different story. Naloxone abruptly plunges an overdosed user into excruciating withdrawal symptoms, he ...

  8. Opioid antagonist - Wikipedia

    en.wikipedia.org/wiki/Opioid_antagonist

    Naltrexone is also a partial inverse agonist, and this property is exploited in treatment of opioid addiction, as a sustained course of low-dose naltrexone can reverse the altered homeostasis which results from long-term abuse of opioid agonist drugs. This is the only treatment available which can reverse the long-term after effects of opioid ...

  9. Post-acute-withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Post-acute-withdrawal_syndrome

    Benzodiazepines, opioids, alcohol, and any other drug may induce prolonged withdrawal and have similar effects, with symptoms sometimes persisting for years after cessation of use. Psychosis including severe anxiety and depression are commonly induced by sustained alcohol, opioid, benzodiazepine, and other drug use which in most cases abates ...

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