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The development of the nervous system in humans, or neural development, or neurodevelopment involves the studies of embryology, developmental biology, and neuroscience. These describe the cellular and molecular mechanisms by which the complex nervous system forms in humans, develops during prenatal development , and continues to develop ...
Defects in neural development can lead to malformations such as holoprosencephaly, and a wide variety of neurological disorders including limb paresis and paralysis, balance and vision disorders, and seizures, [1] and in humans other disorders such as Rett syndrome, Down syndrome and intellectual disability. [2]
Cortical white matter increases from childhood (~9 years) to adolescence (~14 years), most notably in the frontal and parietal cortices. [8] Cortical grey matter development peaks at ~12 years of age in the frontal and parietal cortices, and 14–16 years in the temporal lobes (with the superior temporal cortex being last to mature), peaking at about roughly the same age in both sexes ...
[7] [8] The genes and mechanisms involved in regulating neurogenesis are the subject of intensive research in academic, pharmaceutical, and government settings worldwide. The amount of time required to generate all the neurons of the CNS varies widely across mammals, and brain neurogenesis is not always complete by the time of birth. [3]
Failure of neurulation, especially failure of closure of the neural tube are among the most common and disabling birth defects in humans, occurring in roughly 1 in every 500 live births. [42] Failure of the rostral end of the neural tube to close results in anencephaly, or lack of brain development, and is most often fatal. [43]
The first stage of development runs from birth to 18 months and thus covers the infancy period. The conflict which Erikson identified during this time was trust vs mistrust. During this vulnerable point in the child's life, they are faced with uncertainties in the world and are therefore reliant on their caregiver.
Physical development. Infants are usually born weighing between 5 pounds 8 ounces (2,500 g) and 8 pounds 13 ounces (4,000 g), but infants born prematurely often weigh less. [17] Newborns typically lose 7–10% of their birth weight in the first few days, but they usually regain it within two weeks. [17]
Synaptic pruning, a phase in the development of the nervous system, is the process of synapse elimination that occurs between early childhood and the onset of puberty in many mammals, including humans. [1] Pruning starts near the time of birth and continues into the late-20s. [2]