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Common side effects include hair loss, vomiting, blood in the urine, infections, and kidney problems. [2] Other severe side effects include bone marrow suppression and decreased level of consciousness. [2] Use during pregnancy will likely result in harm to the baby. [2] Ifosfamide is in the alkylating agent and nitrogen mustard family of ...
Bone marrow suppression is a serious side effect of chemotherapy and certain drugs affecting the immune system such as azathioprine. [2] The risk is especially high in cytotoxic chemotherapy for leukemia. In the case of non-small-cell lung cancer, myelosuppression predisposition was shown to be modulated by enhancer mutations. [3]
Common side effects include nausea and bone marrow suppression. [7] Other severe side effects may include anaphylaxis and the development of other cancers. [7] Use during pregnancy may result in harm to the fetus. [8] Melphalan belongs to the class of nitrogen mustard alkylating agents. [7] It works by interfering with the creation of DNA and ...
In conventional chemotherapy, a dose close to the maximum tolerated dose is administered in a bolus manner to achieve cytotoxic effects on tumor cells. [5] However, the side effects are often significant as the cytotoxic agents also kill the fast-dividing cells normally present in the body, such as bone marrow cells and epithelial cells of the gastrointestinal tract. [6]
Common side effects include bone marrow suppression, vomiting, diarrhea, liver problems, rash, ulcer formation in the mouth, and bleeding. [2] Other serious side effects include loss of consciousness, lung disease, and allergic reactions. [2] Use during pregnancy may harm the baby. [2]
Gemcitabine is a chemotherapy drug that works by killing any cells that are dividing. [10] Cancer cells divide rapidly and so are targeted at higher rates by gemcitabine, but many essential cells also divide rapidly, including cells in skin, the scalp, the stomach lining, and bone marrow, resulting in adverse effects. [16]: 265
Severe side effects include low blood platelets, low white blood cells, and blood clots. [8] The dose may need to be adjusted in people with kidney problems . [ 8 ] Lenalidomide is closely related to thalidomide , which is known to cause severe birth defects, so its use during pregnancy is very likely to harm the fetus.
Common side effects include diarrhea, vomiting, bone marrow suppression, hair loss, shortness of breath, and fever. [8] Other severe side effects include blood clots, colon inflammation, and allergic reactions. [8] Those with two copies of the UGT1A1*28 gene variant are at higher risk for side effects. [8]