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The axolotl is less commonly used than other vertebrates, but is still a classical model for examining regeneration and neurogenesis. Though the axolotl has made its place in biomedical research in terms of limb regeneration, [19] [20] the model organism has displayed a robust ability to generate new neurons following damage.
The development of the nervous system in humans, or neural development, or neurodevelopment involves the studies of embryology, developmental biology, and neuroscience.These describe the cellular and molecular mechanisms by which the complex nervous system forms in humans, develops during prenatal development, and continues to develop postnatally.
It is hypothesized in [66] that the growing structure copies the axonal development of the human brain: the earliest developing connections (axonal fibers) are common at most of the subjects, and the subsequently developing connections have larger and larger variance, because their variances are accumulated in the process of axonal development.
These organisms can represent a model for the genetic analysis of adult neurogenesis and brain regeneration. There has been research that discuss how the study of “damage-responsive progenitor cells” in Drosophila can help to identify regenerative neurogenesis and how to find new ways to increase brain rebuilding.
The nervous system is divided by neurologists into two parts: the central nervous system (which consists of the brain and spinal cord) and the peripheral nervous system (which consists of cranial and spinal nerves along with their associated ganglia). While the peripheral nervous system has an intrinsic ability for repair and regeneration, the ...
For example, motor neurons, which travel from the spinal cord to the muscle, can have axons up to a meter in length in humans. The longest axon in the human body belongs to the Sciatic Nerve and runs from the great toe to the base of the spinal cord. These are archetypal examples of neural pathways. [citation needed]
The infant brain will increase in size by a factor of up to 5 by adulthood, reaching a final size of approximately 86 (± 8) billion neurons. [4] Two factors contribute to this growth: the growth of synaptic connections between neurons and the myelination of nerve fibers ; the total number of neurons, however, remains the same.
In neural sprouting, new branches are formed from existing neurons, which can extend towards areas of injury or disease. These new branches can form new connections with other neurons, allowing the brain to redirect inputs to undamaged areas and compensate for the loss of function in the damaged area. [ 3 ]