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  2. Stratum corneum - Wikipedia

    en.wikipedia.org/wiki/Stratum_corneum

    The human stratum corneum comprises several levels of flattened corneocytes that are divided into two layers: the stratum disjunctum and stratum compactum. The skin's protective acid mantle and lipid barrier sit on top of the stratum disjunctum. [5] The stratum disjunctum is the uppermost and loosest layer of skin. The stratum compactum is the ...

  3. Epidermis - Wikipedia

    en.wikipedia.org/wiki/Epidermis

    The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermis layer provides a barrier to infection from environmental pathogens [2] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss.

  4. Stratified squamous epithelium - Wikipedia

    en.wikipedia.org/wiki/Stratified_squamous_epithelium

    It forms the outermost layer of the skin and the inner lining of the mouth, esophagus and vagina. [2] In the epidermis of skin in mammals, reptiles, and birds, the layer of keratin in the outer layer of the stratified squamous epithelial surface is named the stratum corneum. Stratum corneum is made up of squamous cells which are keratinized and ...

  5. Human skin - Wikipedia

    en.wikipedia.org/wiki/Human_skin

    [48] [49] [50] Research confirms that nanoparticles larger than 40 nm do not penetrate the skin past the stratum corneum. [48] Most particles that do penetrate will diffuse through skin cells, but some will travel down hair follicles and reach the dermis layer. The permeability of skin relative to different shapes of nanoparticles has also been ...

  6. Dermis - Wikipedia

    en.wikipedia.org/wiki/Dermis

    The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...

  7. Skin - Wikipedia

    en.wikipedia.org/wiki/Skin

    The mammalian epidermis always possesses at least a stratum germinativum and stratum corneum, but the other intermediate layers found in humans are not always distinguishable. Hair is a distinctive feature of mammalian skin, while feathers are (at least among living species) similarly unique to birds. [23]

  8. Skin sloughing - Wikipedia

    en.wikipedia.org/wiki/Skin_sloughing

    The topmost layer is called the stratum corneum. During sloughing, it is this layer that is removed. [ 1 ] As cells progress through the various layers to reach the stratum corneum, they undergo a process called cornification which transforms keratinocytes to corneocytes, effectively killing them.

  9. Integumentary system - Wikipedia

    en.wikipedia.org/wiki/Integumentary_system

    The human epidermis is composed of stratified squamous epithelial cells, which further break down into four to five layers: the stratum corneum, stratum granulosum, stratum spinosum and stratum basale. Where the skin is thicker, such as in the palms and soles, there is an extra layer of skin between the stratum corneum and the stratum ...