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Glimepiride is an antidiabetic medication within the sulfonylurea class, primarily prescribed for the management of type 2 diabetes. [ 1 ] [ 2 ] It is regarded as a second-line option compared to metformin , due to metformin's well-established safety and efficacy. [ 1 ]
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Glipizide, sold under the brand name Glucotrol among others, is an anti-diabetic medication of the sulfonylurea class used to treat type 2 diabetes. [1] [2] It is used together with a diabetic diet and exercise.
Drugs used in diabetes treat types of diabetes mellitus by decreasing glucose levels in the blood.With the exception of insulin, most GLP-1 receptor agonists (liraglutide, exenatide, and others), and pramlintide, all diabetes medications are administered orally and are thus called oral hypoglycemic agents or oral antihyperglycemic agents.
There are a large number of natural products with alpha-glucosidase inhibitor action [6] [7] [1]. For example, research has shown the culinary mushroom Maitake (Grifola frondosa) has a hypoglycemic effect.
In 1909, Halbert P. Gillette explained about the state of the art around time clocks in those days: IBM time clock. Time clocks.—Such an appliance which may not, in general, be used in the field, but which is of immense value in the office and particularly in a shop, is the time clock.
US sales of the drug were of $2.2 billion in 2006. [47] Sales in 2Q 2007 down 22% compared to 2006. [48] 4Q 2007 sales down to $252 million. [49] Though sales have gone down since 2007 due to safety concerns, Avandia sales for 2009 totalled $1.2 billion worldwide. [50]
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