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Differentiated adipocytes in a 3T3-L1 cell line stained with Oil Red O. 3T3-L1 is a sub clonal cell line derived from the original 3T3 Swiss albino cell line of 1962. The 3T3 original cell line was isolated from a mouse embryo and propagated for this specific line of 3T3 cells is used to study adipose tissue-related diseases and dysfunctions.
NIH-3T3 fibroblasts in cell culture.. 3T3 cells are several cell lines of mouse embryonic fibroblasts.The original 3T3 cell line (3T3-Swiss albino) was established in 1962 by two scientists then at the Department of Pathology in the New York University School of Medicine, George Todaro and Howard Green.
[1] Cellular differentiation is the process in which a stem cell changes from one type to a differentiated one. [2] [3] Usually, the cell changes to a more specialized type. Differentiation happens multiple times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types
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ETV6-NTRK3 gene fusion is the translocation of genetic material between the ETV6 gene located on the short arm (designated p) of chromosome 12 at position p13.2 (i.e. 12p13.2) and the NTRK3 gene located on the long arm (designated q) of chromosome 15 at position q25.3 (i.e. 15q25.3) to create the (12;15)(p13;q25) fusion gene, ETV6-NTRK3.
Some of the pathways that have shown interaction in dedifferentiation are MSX1, Notch 1, BMP, and Wnt/β-Catenin. MSx1 , a gene that is a member of the homeobox family, encodes a transcriptional repressor that can prevent differentiation in epithelial and mesenchymal progenitor cell types. This repressor would be able to keep cells ...
Some of the earliest ideas and mathematical descriptions on how physical processes and constraints affect biological growth, and hence natural patterns such as the spirals of phyllotaxis, were written by D'Arcy Wentworth Thompson in his 1917 book On Growth and Form [2] [3] [note 1] and Alan Turing in his The Chemical Basis of Morphogenesis (1952). [6]
DIF-1 and DIF-3 are related in structure and function. DIF-3 is formed from the first step in the breakdown of DIF-1. In this state DIF-3 only performs about 3.5% as much of the activity of its predecessor. DIF-2 is unrelated to DIFs -1 and -3, but it works 40% as well as DIF-1 does to induce differentiation in stalk cells.