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2,6-Dichloropyridine is a chloropyridine with the formula C 5 H 3 Cl 2 N. A white solid, it is one of six isomers of dichloropyridine . It serves as a precursor to the antibiotic enoxacin , [ 2 ] as well as the drug and anpirtoline and the antifungal liranaftate .
Dichloropyridines are organic compounds with the formula Cl 2 C 5 H 3 N, consisting of a pyridine ring substituted with two chlorides. [1] Six isomers are known. They are white or colorless, most are solids at room temperature.
A major use of 2-chloropyridine is the production of production of the fungicide pyrithione. Reaction of 4-chloropyridine with thioglycolic acid gives pyridylmercaptoacetic acid , a step in the production of cephalosporin antibiotics.
Some dichlorotoluenes are precursors to commercial pesticides. 2,4-Dichlorotoluene is the precursor to pyrifenox, butafenacil, and the pyrazole derivatives pyrazoxyfen and [pyrazolynate]]. The 2,6 isomer is a precursor to dichlobenil (2,6-dichlorobenzonitrile). 3,5-Dichlorotoluene is used to prepare propyzamide. [2]
2,6-Dichloroquinone-4-chloroimide (Gibbs reagent) is an organic compound used as an colorimetric indicator to detect phenolic compounds. [1] Upon reaction with phenol itself, 2,6-dichlorophenolindophenol is formed, [ 2 ] a chemical that is used as a redox indicator .
In these conversions, chloride is displaced. [2] Pyrithione, the conjugate base of 2-mercaptopyridine-N-oxide, is a fungicide found in some shampoos. Oxidation 2-chloropyridine gives 2-chloropyridine-N-oxide. [5] The antihistamine pheniramine may be generated via the reaction of phenylacetonitrile with 2-chloropyridine in the presence of a base ...
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U-47700 is an agonist of the μ-opioid receptor (K i 11.1 ± 0.4 nM) and possesses significantly lower affinity for the κ-opioid receptor (K i = 287 ± 24 nM) and δ-opioid receptor (K i = 1220 ± 82 nM). U-47700 is approximately 10-fold more potent than morphine in rats, although the binding of U-47700 is 2–4 times weaker than morphine at ...