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  2. Glipizide - Wikipedia

    en.wikipedia.org/wiki/Glipizide

    Glipizide, sold under the brand name Glucotrol among others, is an anti-diabetic medication of the sulfonylurea class used to treat type 2 diabetes. [ 1 ] [ 2 ] It is used together with a diabetic diet and exercise.

  3. Signs and symptoms of cancer - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of_cancer

    Signs and symptoms are not mutually exclusive, for example a subjective feeling of fever can be noted as sign by using a thermometer that registers a high reading. [7] Because many symptoms of cancer are gradual in onset and general in nature, cancer screening (also called cancer surveillance) is a key public health priority. This may include ...

  4. GLP-1 receptor agonist - Wikipedia

    en.wikipedia.org/wiki/GLP-1_receptor_agonist

    They are also a first-line treatment for people with both type 2 diabetes and kidney disease. Both types of medication can be combined with metformin . [ 8 ] [ 9 ] One advantage of GLP-1 agonists over older insulin secretagogues , such as sulfonylureas or meglitinides , is that they have a lower risk of causing hypoglycemia . [ 10 ]

  5. Thiazolidinedione - Wikipedia

    en.wikipedia.org/wiki/Thiazolidinedione

    Thiazolidinedione ligand dependent transactivation is responsible for the majority of anti-diabetic effects. The activated PPAR/RXR heterodimer binds to peroxisome proliferator hormone response elements upstream of target genes in complex with a number of coactivators such as nuclear receptor coactivator 1 and CREB binding protein, this causes upregulation of genes (for a full list see PPARγ):

  6. CYP2C9 - Wikipedia

    en.wikipedia.org/wiki/CYP2C9

    1559 72303 Ensembl ENSG00000138109 ENSMUSG00000067231 UniProt P11712 n/a RefSeq (mRNA) NM_000771 NM_028191 RefSeq (protein) NP_000762 n/a Location (UCSC) Chr 10: 94.94 – 94.99 Mb Chr 19: 39.05 – 39.08 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cytochrome P450 family 2 subfamily C member 9 (abbreviated CYP2C9) is an enzyme protein. The enzyme is involved in the metabolism, by ...

  7. The Palace clarifies that while undisclosed in its form, the monarch does not have prostate cancer, although the disease was found during his prostate procedure. The king steps back from his ...

  8. Sulfonamide (medicine) - Wikipedia

    en.wikipedia.org/wiki/Sulfonamide_(medicine)

    The moiety is also present in other medications that are not antimicrobials, including thiazide diuretics (including hydrochlorothiazide, metolazone, and indapamide, among others), loop diuretics (including furosemide, bumetanide, and torsemide), acetazolamide, sulfonylureas (including glipizide, glyburide, among others), and some COX-2 ...

  9. Diabetes medication - Wikipedia

    en.wikipedia.org/wiki/Diabetes_medication

    Insulins are typically characterized by the rate at which they are metabolized by the body, yielding different peak times and durations of action. [4] Faster-acting insulins peak quickly and are subsequently metabolized, while longer-acting insulins tend to have extended peak times and remain active in the body for more significant periods.