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A dendritic spine (or spine) is a small membrane protrusion from a neuron's dendrite that typically receives input from a single axon at the synapse.Dendritic spines serve as a storage site for synaptic strength and help transmit electrical signals to the neuron's cell body.
There are many recognized spinal diseases, some more common than others. Spinal disease also includes cervical spine diseases, which are diseases in the vertebrae of the neck. A lot of flexibility exists within the cervical spine and because of that, it is common for an individual to damage that area, especially over a long period of time.
An apical dendrite is a dendrite that emerges from the apex of a pyramidal cell. [1] Apical dendrites are one of two primary categories of dendrites, and they distinguish the pyramidal cells from spiny stellate cells in the cortices.
However, dendritic filopodia can take on spine-like morphologies even without post-synaptic density proteins, pointing to actin remodeling as the primary process responsible for the development of spines from filopodia. Cytoskeletal analyses of spines versus filopodia have found that a spine-like morphology is associated with higher numbers of ...
The spine apparatus’ ability to release calcium into the cytosol is thought to contribute to the development of synaptic plasticity. This was first shown in an experiment using synaptopodin(SP)-deficient mice, which do not show a spine apparatus in dendritic spines. [8] These SP-deficient mice showed a decrease in long-term potentiation (LTP ...
Dendritic arborization, also known as dendritic branching, is a multi-step biological process by which neurons form new dendritic trees and branches to create new synapses. [1] Dendrites in many organisms assume different morphological patterns of branching.
The bases of denticulate ligaments arise in the pia mater and are firmly attached to the arachnoid mater and dura mater at the apex. [2] The denticulate ligaments extend across the subarachnoid space between anterior nerve roots and posterior nerve roots, piercing the intervening spinal arachnoid mater to reach the dura.
Blastic plasmacytoid dendritic cell neoplasm is an aggressive malignancy with features of cutaneous lymphoma (e.g. malignant plasmacytoid dendritic cell infiltrations into the skin to form single or multiple lesions) and/or leukemia (i.e. malignant plasmacytoid dendritic cells in blood and bone marrow). [2]